BindingDB logo
myBDB logout

null

SMILES: COC(=O)c1cccc(c1)-n1ccc2cnc(Nc3cc(OC)c(OC)c(OC)c3)nc12

InChI Key: InChIKey=WBGWXADQTCLJPH-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50184012   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Focal adhesion kinase 1


(Homo sapiens (Human))		BDBM50184012
PNG
(CHEMBL381374 | methyl 3-(2-(3,4,5-trimethoxyphenyl...)
Show SMILES COC(=O)c1cccc(c1)-n1ccc2cnc(Nc3cc(OC)c(OC)c(OC)c3)nc12
Show InChI InChI=1S/C23H22N4O5/c1-29-18-11-16(12-19(30-2)20(18)31-3)25-23-24-13-15-8-9-27(21(15)26-23)17-7-5-6-14(10-17)22(28)32-4/h5-13H,1-4H3,(H,24,25,26)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 1.51E+3n/an/an/an/an/an/a



Genomics Institute of the Novartis Research Foundation (GNF)

Curated by ChEMBL


Assay Description
Inhibition of FAK

Bioorg Med Chem Lett 16: 2689-92 (2006)


Article DOI: 10.1016/j.bmcl.2006.02.032
BindingDB Entry DOI: 10.7270/Q2NK3DN0
More data for this
Ligand-Target Pair