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SMILES: COc1cc(Nc2ncc3ccn(-c4cccc(c4)C(=O)NCCO)c3n2)cc(OC)c1OC

InChI Key: InChIKey=ZGIIRYMLQQZMJY-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50184033   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Focal adhesion kinase 1


(Homo sapiens (Human))		BDBM50184033
PNG
(CHEMBL379279 | N-(2-hydroxyethyl)-3-(2-(3,4,5-trim...)
Show SMILES COc1cc(Nc2ncc3ccn(-c4cccc(c4)C(=O)NCCO)c3n2)cc(OC)c1OC
Show InChI InChI=1S/C24H25N5O5/c1-32-19-12-17(13-20(33-2)21(19)34-3)27-24-26-14-16-7-9-29(22(16)28-24)18-6-4-5-15(11-18)23(31)25-8-10-30/h4-7,9,11-14,30H,8,10H2,1-3H3,(H,25,31)(H,26,27,28)
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n/an/a 434n/an/an/an/an/an/a



Genomics Institute of the Novartis Research Foundation (GNF)

Curated by ChEMBL


Assay Description
Inhibition of FAK

Bioorg Med Chem Lett 16: 2689-92 (2006)


Article DOI: 10.1016/j.bmcl.2006.02.032
BindingDB Entry DOI: 10.7270/Q2NK3DN0
More data for this
Ligand-Target Pair