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SMILES: COC[C@H]1CCCN1C1=C(C(=O)OC)[C@@]2(Sc3ccccc3[C@H]12)C(=O)OC

InChI Key: InChIKey=UNAMQNCWXYHUFL-ASNKJTAVSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50184079   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Reverse transcriptase/RNaseH


(Human immunodeficiency virus 1)		BDBM50184079
PNG
((2aR,7aR)-2-((R)-2-methoxymethyl-pyrrolidin-1-yl)-...)
Show SMILES COC[C@H]1CCCN1C1=C(C(=O)OC)[C@@]2(Sc3ccccc3[C@H]12)C(=O)OC |c:9|
Show InChI InChI=1S/C20H23NO5S/c1-24-11-12-7-6-10-21(12)17-15-13-8-4-5-9-14(13)27-20(15,19(23)26-3)16(17)18(22)25-2/h4-5,8-9,12,15H,6-7,10-11H2,1-3H3/t12-,15-,20-/m1/s1
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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 3.80E+4n/an/an/an/an/an/a



NIH

Curated by ChEMBL


Assay Description
Inhibition of wild type HIV1 reverse transcriptase in 293T cells

Bioorg Med Chem Lett 16: 3034-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.02.049
BindingDB Entry DOI: 10.7270/Q2DN45VP
More data for this
Ligand-Target Pair