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SMILES: CCCNC(=O)[C@@H](NC(=O)c1ccc(NC(=O)c2ccccc2-c2ccc(cc2)C(F)(F)F)nc1)c1ccccc1

InChI Key: InChIKey=HWAOBTBZQZRULC-MHZLTWQESA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50184127   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Microsomal triglyceride transfer protein large subunit


(Homo sapiens (Human))		BDBM50184127
PNG
(CHEMBL207443 | N-((S)-Phenyl-propylcarbamoyl-methy...)
Show SMILES CCCNC(=O)[C@@H](NC(=O)c1ccc(NC(=O)c2ccccc2-c2ccc(cc2)C(F)(F)F)nc1)c1ccccc1
Show InChI InChI=1S/C31H27F3N4O3/c1-2-18-35-30(41)27(21-8-4-3-5-9-21)38-28(39)22-14-17-26(36-19-22)37-29(40)25-11-7-6-10-24(25)20-12-15-23(16-13-20)31(32,33)34/h3-17,19,27H,2,18H2,1H3,(H,35,41)(H,38,39)(H,36,37,40)/t27-/m0/s1
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n/an/a 2.53n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of MTP in canine liver microsomes

Bioorg Med Chem Lett 16: 3039-42 (2006)


Article DOI: 10.1016/j.bmcl.2006.02.058
BindingDB Entry DOI: 10.7270/Q2D21X68
More data for this
Ligand-Target Pair