BDBM50184138 4'-trifluoromethyl-biphenyl-2-carboxylic acid [2-methyl-4-((S)-2-oxo-1-phenyl-2-pyrrolidin-1-yl-ethylcarbamoyl)-phenyl]-amide::CHEMBL209508

SMILES: Cc1cc(ccc1NC(=O)c1ccccc1-c1ccc(cc1)C(F)(F)F)C(=O)N[C@H](C(=O)N1CCCC1)c1ccccc1

InChI Key: InChIKey=RKEABJOATNXQTO-PMERELPUSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50184138   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Microsomal triglyceride transfer protein (Homo sapiens (Human))	BDBM50184138 (4'-trifluoromethyl-biphenyl-2-carboxylic acid [2-m...) Show SMILES Cc1cc(ccc1NC(=O)c1ccccc1-c1ccc(cc1)C(F)(F)F)C(=O)N[C@H](C(=O)N1CCCC1)c1ccccc1 Show InChI InChI=1S/C34H30F3N3O3/c1-22-21-25(31(41)39-30(24-9-3-2-4-10-24)33(43)40-19-7-8-20-40)15-18-29(22)38-32(42)28-12-6-5-11-27(28)23-13-16-26(17-14-23)34(35,36)37/h2-6,9-18,21,30H,7-8,19-20H2,1H3,(H,38,42)(H,39,41)/t30-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.37	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of MTP in canine liver microsomes				Bioorg Med Chem Lett 16: 3039-42 (2006) Article DOI: 10.1016/j.bmcl.2006.02.058 BindingDB Entry DOI: 10.7270/Q2D21X68
					More data for this Ligand-Target Pair