BDBM50184147 4'-trifluoromethyl-biphenyl-2-carboxylic acid {4-[((S)-benzylcarbamoyl-phenyl-methyl)-carbamoyl]-2-methyl-phenyl}-amide::CHEMBL210704

SMILES: Cc1cc(ccc1NC(=O)c1ccccc1-c1ccc(cc1)C(F)(F)F)C(=O)N[C@H](C(=O)NCc1ccccc1)c1ccccc1

InChI Key: InChIKey=DCVABLOPNUECRE-XIFFEERXSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50184147   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Microsomal triglyceride transfer protein (Homo sapiens (Human))	BDBM50184147 (4'-trifluoromethyl-biphenyl-2-carboxylic acid {4-[...) Show SMILES Cc1cc(ccc1NC(=O)c1ccccc1-c1ccc(cc1)C(F)(F)F)C(=O)N[C@H](C(=O)NCc1ccccc1)c1ccccc1 Show InChI InChI=1S/C37H30F3N3O3/c1-24-22-28(34(44)43-33(27-12-6-3-7-13-27)36(46)41-23-25-10-4-2-5-11-25)18-21-32(24)42-35(45)31-15-9-8-14-30(31)26-16-19-29(20-17-26)37(38,39)40/h2-22,33H,23H2,1H3,(H,41,46)(H,42,45)(H,43,44)/t33-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of MTP in canine liver microsomes				Bioorg Med Chem Lett 16: 3039-42 (2006) Article DOI: 10.1016/j.bmcl.2006.02.058 BindingDB Entry DOI: 10.7270/Q2D21X68
					More data for this Ligand-Target Pair