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SMILES: FC(F)(F)c1ccc(cc1)-c1ccccc1C(=O)NCc1ccc(cc1)C(=O)N[C@H](C(=O)NCc1ccccc1)c1ccccc1

InChI Key: InChIKey=HJHLNHFORMMEGB-XIFFEERXSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50184152   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Microsomal triglyceride transfer protein large subunit


(Homo sapiens (Human))		BDBM50184152
PNG
(4'-trifluoromethyl-biphenyl-2-carboxylic acid 4-[(...)
Show SMILES FC(F)(F)c1ccc(cc1)-c1ccccc1C(=O)NCc1ccc(cc1)C(=O)N[C@H](C(=O)NCc1ccccc1)c1ccccc1
Show InChI InChI=1S/C37H30F3N3O3/c38-37(39,40)30-21-19-27(20-22-30)31-13-7-8-14-32(31)35(45)41-24-26-15-17-29(18-16-26)34(44)43-33(28-11-5-2-6-12-28)36(46)42-23-25-9-3-1-4-10-25/h1-22,33H,23-24H2,(H,41,45)(H,42,46)(H,43,44)/t33-/m0/s1
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Article
PubMed
n/an/a 2.97n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of MTP in canine liver microsomes

Bioorg Med Chem Lett 16: 3039-42 (2006)


Article DOI: 10.1016/j.bmcl.2006.02.058
BindingDB Entry DOI: 10.7270/Q2D21X68
More data for this
Ligand-Target Pair