BDBM50184185 3-chloro-3'-fluoro-4'-[(4-piperidin-1-ylmethyl-pyridin-2-ylamino)-methyl]-biphenyl-2-carboxylic acid methyl ester::CHEMBL377440

SMILES: COC(=O)c1c(Cl)cccc1-c1ccc(CNc2cc(CN3CCCCC3)ccn2)c(F)c1

InChI Key: InChIKey=FQRSFCOCYJWHNX-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50184185   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
B1 bradykinin receptor (Homo sapiens (Human))	BDBM50184185 (3-chloro-3'-fluoro-4'-[(4-piperidin-1-ylmethyl-pyr...) Show SMILES COC(=O)c1c(Cl)cccc1-c1ccc(CNc2cc(CN3CCCCC3)ccn2)c(F)c1 Show InChI InChI=1S/C26H27ClFN3O2/c1-33-26(32)25-21(6-5-7-22(25)27)19-8-9-20(23(28)15-19)16-30-24-14-18(10-11-29-24)17-31-12-3-2-4-13-31/h5-11,14-15H,2-4,12-13,16-17H2,1H3,(H,29,30)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	611	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity to human BK1 receptor				Bioorg Med Chem Lett 16: 2791-5 (2006) Article DOI: 10.1016/j.bmcl.2006.01.112 BindingDB Entry DOI: 10.7270/Q28915GX
					More data for this Ligand-Target Pair