BDBM50184197 4-{6-[(3,3'-difluoro-2'-methoxycarbonyl-biphenyl-4-ylmethyl)-amino]-pyridine-3-carbonyl}-piperazine-1-carboxylic acid methyl ester::CHEMBL383089
SMILES: COC(=O)N1CCN(CC1)C(=O)c1ccc(NCc2ccc(cc2F)-c2cccc(F)c2C(=O)OC)nc1
InChI Key: InChIKey=JCHQHSSUQMZRIU-UHFFFAOYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Bradykinin B1 receptor (Homo sapiens (Human)) | BDBM50184197 (4-{6-[(3,3'-difluoro-2'-methoxycarbonyl-biphenyl-4...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 34 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Binding affinity to human BK1 receptor | Bioorg Med Chem Lett 16: 2791-5 (2006) Article DOI: 10.1016/j.bmcl.2006.01.112 BindingDB Entry DOI: 10.7270/Q28915GX | |||||||||||
More data for this Ligand-Target Pair |