BDBM50184201 4'-{[5-(4-sec-butyl-piperazine-1-carbonyl)-pyridin-2-ylamino]-methyl}-3,3'-difluoro-biphenyl-2-carboxylica acid methyl ester::CHEMBL208991
SMILES: CCC(C)N1CCN(CC1)C(=O)c1ccc(NCc2ccc(cc2F)-c2cccc(F)c2C(=O)OC)nc1
InChI Key: InChIKey=TXCQAQYYRPLPMQ-UHFFFAOYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Bradykinin B1 receptor (Homo sapiens (Human)) | BDBM50184201 (4'-{[5-(4-sec-butyl-piperazine-1-carbonyl)-pyridin...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Binding affinity to human BK1 receptor | Bioorg Med Chem Lett 16: 2791-5 (2006) Article DOI: 10.1016/j.bmcl.2006.01.112 BindingDB Entry DOI: 10.7270/Q28915GX | |||||||||||
More data for this Ligand-Target Pair |