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BDBM50184384 6-hydroxymethyl-3-[(Z)-3-isobutyl-5-methylhexylidene]-6-pivaloyloxymethyl-tetrahydro-2-pyranone::CHEMBL206605

SMILES: CC(C)CC(C\C=C1\CCC(CO)(COC(=O)C(C)(C)C)OC1=O)CC(C)C

InChI Key: InChIKey=SEXDAQXIGRTJGA-OCKHKDLRSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50184384   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Protein kinase C alpha type


(Homo sapiens (Human))
BDBM50184384
PNG
(6-hydroxymethyl-3-[(Z)-3-isobutyl-5-methylhexylide...)
Show SMILES CC(C)CC(C\C=C1\CCC(CO)(COC(=O)C(C)(C)C)OC1=O)CC(C)C
Show InChI InChI=1S/C23H40O5/c1-16(2)12-18(13-17(3)4)8-9-19-10-11-23(14-24,28-20(19)25)15-27-21(26)22(5,6)7/h9,16-18,24H,8,10-15H2,1-7H3/b19-9-
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
28n/an/an/an/an/an/an/an/a



Research Institute of Pharmaceutical Sciences

Curated by ChEMBL


Assay Description
Displacement of [20-3H]PDBu from recombinant PKC alpha in presence of phosphatidylserine


J Med Chem 49: 2028-36 (2006)


Article DOI: 10.1021/jm0509391
BindingDB Entry DOI: 10.7270/Q27D2TQ1
More data for this
Ligand-Target Pair