BDBM50184434 2-Hydroxy-7-methyl-5,6,7,8,9,14-hexahydrodibenzo[d,g]azecine::CHEMBL382010

SMILES: CN1CCc2ccccc2Cc2cc(O)ccc2CC1

InChI Key: InChIKey=PWYCTCPWHXJEDU-UHFFFAOYSA-N

Data: 7 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50184434   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50184434 (2-Hydroxy-7-methyl-5,6,7,8,9,14-hexahydrodibenzo[d...) Show SMILES CN1CCc2ccccc2Cc2cc(O)ccc2CC1 Show InChI InChI=1S/C18H21NO/c1-19-10-8-14-4-2-3-5-16(14)12-17-13-18(20)7-6-15(17)9-11-19/h2-7,13,20H,8-12H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Schiller-Universität Jena Curated by ChEMBL					Assay Description Inhibition of D1 dopamine receptor in HEK 293 cells by intracellular calcium assay				J Med Chem 49: 2110-6 (2006) Article DOI: 10.1021/jm051237e BindingDB Entry DOI: 10.7270/Q2ZW1KHD
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50184434 (2-Hydroxy-7-methyl-5,6,7,8,9,14-hexahydrodibenzo[d...) Show SMILES CN1CCc2ccccc2Cc2cc(O)ccc2CC1 Show InChI InChI=1S/C18H21NO/c1-19-10-8-14-4-2-3-5-16(14)12-17-13-18(20)7-6-15(17)9-11-19/h2-7,13,20H,8-12H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Schiller-Universität Jena Curated by ChEMBL					Assay Description Displacement of [3H]SCH 23390 from D1 dopamine receptor				J Med Chem 49: 2110-6 (2006) Article DOI: 10.1021/jm051237e BindingDB Entry DOI: 10.7270/Q2ZW1KHD
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50184434 (2-Hydroxy-7-methyl-5,6,7,8,9,14-hexahydrodibenzo[d...) Show SMILES CN1CCc2ccccc2Cc2cc(O)ccc2CC1 Show InChI InChI=1S/C18H21NO/c1-19-10-8-14-4-2-3-5-16(14)12-17-13-18(20)7-6-15(17)9-11-19/h2-7,13,20H,8-12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Schiller-Universität Jena Curated by ChEMBL					Assay Description Inhibition of D2L dopamine receptor in HEK 293 cells by intracellular calcium assay				J Med Chem 49: 2110-6 (2006) Article DOI: 10.1021/jm051237e BindingDB Entry DOI: 10.7270/Q2ZW1KHD
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50184434 (2-Hydroxy-7-methyl-5,6,7,8,9,14-hexahydrodibenzo[d...) Show SMILES CN1CCc2ccccc2Cc2cc(O)ccc2CC1 Show InChI InChI=1S/C18H21NO/c1-19-10-8-14-4-2-3-5-16(14)12-17-13-18(20)7-6-15(17)9-11-19/h2-7,13,20H,8-12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	36.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Schiller-Universität Jena Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from D2L dopamine receptor				J Med Chem 49: 2110-6 (2006) Article DOI: 10.1021/jm051237e BindingDB Entry DOI: 10.7270/Q2ZW1KHD
					More data for this Ligand-Target Pair
D(1B) dopamine receptor (Homo sapiens (Human))	BDBM50184434 (2-Hydroxy-7-methyl-5,6,7,8,9,14-hexahydrodibenzo[d...) Show SMILES CN1CCc2ccccc2Cc2cc(O)ccc2CC1 Show InChI InChI=1S/C18H21NO/c1-19-10-8-14-4-2-3-5-16(14)12-17-13-18(20)7-6-15(17)9-11-19/h2-7,13,20H,8-12H2,1H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	37.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Schiller-Universität Jena Curated by ChEMBL					Assay Description Inhibition of D5 dopamine receptor in HEK 293 cells by intracellular calcium assay				J Med Chem 49: 2110-6 (2006) Article DOI: 10.1021/jm051237e BindingDB Entry DOI: 10.7270/Q2ZW1KHD
					More data for this Ligand-Target Pair
D(1B) dopamine receptor (Homo sapiens (Human))	BDBM50184434 (2-Hydroxy-7-methyl-5,6,7,8,9,14-hexahydrodibenzo[d...) Show SMILES CN1CCc2ccccc2Cc2cc(O)ccc2CC1 Show InChI InChI=1S/C18H21NO/c1-19-10-8-14-4-2-3-5-16(14)12-17-13-18(20)7-6-15(17)9-11-19/h2-7,13,20H,8-12H2,1H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	42.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Schiller-Universität Jena Curated by ChEMBL					Assay Description Binding affinity to D5 dopamine receptor by radioligand binding assay				J Med Chem 49: 2110-6 (2006) Article DOI: 10.1021/jm051237e BindingDB Entry DOI: 10.7270/Q2ZW1KHD
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50184434 (2-Hydroxy-7-methyl-5,6,7,8,9,14-hexahydrodibenzo[d...) Show SMILES CN1CCc2ccccc2Cc2cc(O)ccc2CC1 Show InChI InChI=1S/C18H21NO/c1-19-10-8-14-4-2-3-5-16(14)12-17-13-18(20)7-6-15(17)9-11-19/h2-7,13,20H,8-12H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	296	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Schiller-Universität Jena Curated by ChEMBL					Assay Description Binding affinity to D3 dopamine receptor by radioligand binding assay				J Med Chem 49: 2110-6 (2006) Article DOI: 10.1021/jm051237e BindingDB Entry DOI: 10.7270/Q2ZW1KHD
					More data for this Ligand-Target Pair