BDBM50184725 CHEMBL3824056

SMILES: Cc1ccc(O)cc1Nc1ccnc2ccc(cc12)C(=O)NCC1CCOCC1

InChI Key: InChIKey=QLSAXYFWMHAMER-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50184725   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase RIPK2 (Homo sapiens (Human))	BDBM50184725 (CHEMBL3824056) Show SMILES Cc1ccc(O)cc1Nc1ccnc2ccc(cc12)C(=O)NCC1CCOCC1 Show InChI InChI=1S/C23H25N3O3/c1-15-2-4-18(27)13-22(15)26-21-6-9-24-20-5-3-17(12-19(20)21)23(28)25-14-16-7-10-29-11-8-16/h2-6,9,12-13,16,27H,7-8,10-11,14H2,1H3,(H,24,26)(H,25,28)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Competitive inhibition of full length FLAG-His-tagged RIP2K (unknown origin) expressed in baculovirus expression system preincubated for 10 mins foll...				J Med Chem 59: 4867-80 (2016) BindingDB Entry DOI: 10.7270/Q2G162SQ
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50184725 (CHEMBL3824056) Show SMILES Cc1ccc(O)cc1Nc1ccnc2ccc(cc12)C(=O)NCC1CCOCC1 Show InChI InChI=1S/C23H25N3O3/c1-15-2-4-18(27)13-22(15)26-21-6-9-24-20-5-3-17(12-19(20)21)23(28)25-14-16-7-10-29-11-8-16/h2-6,9,12-13,16,27H,7-8,10-11,14H2,1H3,(H,24,26)(H,25,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of VEGFR2(unknown origin)				J Med Chem 59: 4867-80 (2016) BindingDB Entry DOI: 10.7270/Q2G162SQ
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50184725 (CHEMBL3824056) Show SMILES Cc1ccc(O)cc1Nc1ccnc2ccc(cc12)C(=O)NCC1CCOCC1 Show InChI InChI=1S/C23H25N3O3/c1-15-2-4-18(27)13-22(15)26-21-6-9-24-20-5-3-17(12-19(20)21)23(28)25-14-16-7-10-29-11-8-16/h2-6,9,12-13,16,27H,7-8,10-11,14H2,1H3,(H,24,26)(H,25,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of p38alpha (unknown origin)				J Med Chem 59: 4867-80 (2016) BindingDB Entry DOI: 10.7270/Q2G162SQ
					More data for this Ligand-Target Pair