BDBM50184754 (E)-methyl-3,6-dioxo-4-docosenoate::CHEMBL425779
SMILES: CCCCCCCCCCCCCCCCC(=O)C=CC(=O)CC(=O)OC
InChI Key: InChIKey=OQTABBSTMSUYST-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
DNA polymerase beta (Homo sapiens (Human)) | BDBM50184754 ((E)-methyl-3,6-dioxo-4-docosenoate | CHEMBL425779) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 8.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Manchester Curated by ChEMBL | Assay Description Inhibition of DNA polymerase beta | Bioorg Med Chem Lett 16: 2877-81 (2006) Article DOI: 10.1016/j.bmcl.2006.03.005 BindingDB Entry DOI: 10.7270/Q25D8RF8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase (alpha/delta/epsilon) (Homo sapiens (Human)) | BDBM50184754 ((E)-methyl-3,6-dioxo-4-docosenoate | CHEMBL425779) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Manchester Curated by ChEMBL | Assay Description Inhibition of DNA polymerase alpha | Bioorg Med Chem Lett 16: 2877-81 (2006) Article DOI: 10.1016/j.bmcl.2006.03.005 BindingDB Entry DOI: 10.7270/Q25D8RF8 | |||||||||||
More data for this Ligand-Target Pair |