BDBM50184770 CHEMBL3823849::US10294227, Code 112

SMILES: CN(C)CC1CCN(CCn2nc(-c3ccc(C)cc3)c3c(N)ncnc23)CC1

InChI Key: InChIKey=AKSZNKRUJCTEIJ-UHFFFAOYSA-N

Data: 22 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 22 hits for monomerid = 50184770   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM50184770 (CHEMBL3823849 | US10294227, Code 112) Show SMILES CN(C)CC1CCN(CCn2nc(-c3ccc(C)cc3)c3c(N)ncnc23)CC1 Show InChI InChI=1S/C22H31N7/c1-16-4-6-18(7-5-16)20-19-21(23)24-15-25-22(19)29(26-20)13-12-28-10-8-17(9-11-28)14-27(2)3/h4-7,15,17H,8-14H2,1-3H3,(H2,23,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1	n/a	n/a	n/a	n/a	n/a	n/a
University of Edinburgh Curated by ChEMBL					Assay Description Inhibition of human mTOR using poly[Glu,Tyr]4:1 as substrate in presence of [gamma-33P]ATP				J Med Chem 59: 4697-710 (2016) BindingDB Entry DOI: 10.7270/Q2B85B2D
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Yes (Homo sapiens (Human))	BDBM50184770 (CHEMBL3823849 | US10294227, Code 112) Show SMILES CN(C)CC1CCN(CCn2nc(-c3ccc(C)cc3)c3c(N)ncnc23)CC1 Show InChI InChI=1S/C22H31N7/c1-16-4-6-18(7-5-16)20-19-21(23)24-15-25-22(19)29(26-20)13-12-28-10-8-17(9-11-28)14-27(2)3/h4-7,15,17H,8-14H2,1-3H3,(H2,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Compound IC50 values were determined from 10-point, 1:3 dilution curves starting at either 100 μM or 10 μM with 10 μM ATP, by Reaction...				Bioorg Med Chem Lett 19: 773-7 (2009) BindingDB Entry DOI: 10.7270/Q27D2XFP
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase receptor Ret (Homo sapiens (Human))	BDBM50184770 (CHEMBL3823849 | US10294227, Code 112) Show SMILES CN(C)CC1CCN(CCn2nc(-c3ccc(C)cc3)c3c(N)ncnc23)CC1 Show InChI InChI=1S/C22H31N7/c1-16-4-6-18(7-5-16)20-19-21(23)24-15-25-22(19)29(26-20)13-12-28-10-8-17(9-11-28)14-27(2)3/h4-7,15,17H,8-14H2,1-3H3,(H2,23,24,25)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1	n/a	n/a	n/a	n/a	n/a	n/a
University of Edinburgh Curated by ChEMBL					Assay Description Inhibition of human RET using poly[Glu,Tyr]4:1 as substrate in presence of [gamma-33P]ATP				J Med Chem 59: 4697-710 (2016) BindingDB Entry DOI: 10.7270/Q2B85B2D
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Homo sapiens (Human))	BDBM50184770 (CHEMBL3823849 | US10294227, Code 112) Show SMILES CN(C)CC1CCN(CCn2nc(-c3ccc(C)cc3)c3c(N)ncnc23)CC1 Show InChI InChI=1S/C22H31N7/c1-16-4-6-18(7-5-16)20-19-21(23)24-15-25-22(19)29(26-20)13-12-28-10-8-17(9-11-28)14-27(2)3/h4-7,15,17H,8-14H2,1-3H3,(H2,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	7.53E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Edinburgh Curated by ChEMBL					Assay Description Inhibition of human ABL using EAIYAAPFAKKK as substrate in presence of [gamma-33P]ATP				J Med Chem 59: 4697-710 (2016) BindingDB Entry DOI: 10.7270/Q2B85B2D
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Fyn (Homo sapiens (Human))	BDBM50184770 (CHEMBL3823849 | US10294227, Code 112) Show SMILES CN(C)CC1CCN(CCn2nc(-c3ccc(C)cc3)c3c(N)ncnc23)CC1 Show InChI InChI=1S/C22H31N7/c1-16-4-6-18(7-5-16)20-19-21(23)24-15-25-22(19)29(26-20)13-12-28-10-8-17(9-11-28)14-27(2)3/h4-7,15,17H,8-14H2,1-3H3,(H2,23,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	913	n/a	n/a	n/a	n/a	n/a	n/a
University of Edinburgh Curated by ChEMBL					Assay Description Inhibition of human FYN using poly[Glu,Tyr]4:1 as substrate in presence of [gamma-33P]ATP				J Med Chem 59: 4697-710 (2016) BindingDB Entry DOI: 10.7270/Q2B85B2D
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50184770 (CHEMBL3823849 | US10294227, Code 112) Show SMILES CN(C)CC1CCN(CCn2nc(-c3ccc(C)cc3)c3c(N)ncnc23)CC1 Show InChI InChI=1S/C22H31N7/c1-16-4-6-18(7-5-16)20-19-21(23)24-15-25-22(19)29(26-20)13-12-28-10-8-17(9-11-28)14-27(2)3/h4-7,15,17H,8-14H2,1-3H3,(H2,23,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1	n/a	n/a	n/a	n/a	n/a	n/a
University of Edinburgh Curated by ChEMBL					Assay Description Inhibition of human KIT using poly[Glu,Tyr]4:1 as substrate in presence of [gamma-33P]ATP				J Med Chem 59: 4697-710 (2016) BindingDB Entry DOI: 10.7270/Q2B85B2D
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50184770 (CHEMBL3823849 | US10294227, Code 112) Show SMILES CN(C)CC1CCN(CCn2nc(-c3ccc(C)cc3)c3c(N)ncnc23)CC1 Show InChI InChI=1S/C22H31N7/c1-16-4-6-18(7-5-16)20-19-21(23)24-15-25-22(19)29(26-20)13-12-28-10-8-17(9-11-28)14-27(2)3/h4-7,15,17H,8-14H2,1-3H3,(H2,23,24,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	303	n/a	n/a	n/a	n/a	n/a	n/a
University of Edinburgh Curated by ChEMBL					Assay Description Inhibition of C-terminal His-tagged full length human SRC expressed in insect cells preincubated for 20 mins using poly[Glu,Tyr]4:1 as substrate meas...				J Med Chem 59: 4697-710 (2016) BindingDB Entry DOI: 10.7270/Q2B85B2D
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Yes (Homo sapiens (Human))	BDBM50184770 (CHEMBL3823849 | US10294227, Code 112) Show SMILES CN(C)CC1CCN(CCn2nc(-c3ccc(C)cc3)c3c(N)ncnc23)CC1 Show InChI InChI=1S/C22H31N7/c1-16-4-6-18(7-5-16)20-19-21(23)24-15-25-22(19)29(26-20)13-12-28-10-8-17(9-11-28)14-27(2)3/h4-7,15,17H,8-14H2,1-3H3,(H2,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	344	n/a	n/a	n/a	n/a	n/a	n/a
University of Edinburgh Curated by ChEMBL					Assay Description Inhibition of human YES using poly[Glu,Tyr]4:1 as substrate in presence of [gamma-33P] ATP				J Med Chem 59: 4697-710 (2016) BindingDB Entry DOI: 10.7270/Q2B85B2D
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Homo sapiens (Human))	BDBM50184770 (CHEMBL3823849 | US10294227, Code 112) Show SMILES CN(C)CC1CCN(CCn2nc(-c3ccc(C)cc3)c3c(N)ncnc23)CC1 Show InChI InChI=1S/C22H31N7/c1-16-4-6-18(7-5-16)20-19-21(23)24-15-25-22(19)29(26-20)13-12-28-10-8-17(9-11-28)14-27(2)3/h4-7,15,17H,8-14H2,1-3H3,(H2,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Compound IC50 values were determined from 10-point, 1:3 dilution curves starting at either 100 μM or 10 μM with 10 μM ATP, by Reaction...				Bioorg Med Chem Lett 19: 773-7 (2009) BindingDB Entry DOI: 10.7270/Q27D2XFP
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Blk (Homo sapiens (Human))	BDBM50184770 (CHEMBL3823849 | US10294227, Code 112) Show SMILES CN(C)CC1CCN(CCn2nc(-c3ccc(C)cc3)c3c(N)ncnc23)CC1 Show InChI InChI=1S/C22H31N7/c1-16-4-6-18(7-5-16)20-19-21(23)24-15-25-22(19)29(26-20)13-12-28-10-8-17(9-11-28)14-27(2)3/h4-7,15,17H,8-14H2,1-3H3,(H2,23,24,25)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Compound IC50 values were determined from 10-point, 1:3 dilution curves starting at either 100 μM or 10 μM with 10 μM ATP, by Reaction...				Bioorg Med Chem Lett 19: 773-7 (2009) BindingDB Entry DOI: 10.7270/Q27D2XFP
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Fgr (Homo sapiens (Human))	BDBM50184770 (CHEMBL3823849 | US10294227, Code 112) Show SMILES CN(C)CC1CCN(CCn2nc(-c3ccc(C)cc3)c3c(N)ncnc23)CC1 Show InChI InChI=1S/C22H31N7/c1-16-4-6-18(7-5-16)20-19-21(23)24-15-25-22(19)29(26-20)13-12-28-10-8-17(9-11-28)14-27(2)3/h4-7,15,17H,8-14H2,1-3H3,(H2,23,24,25)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Compound IC50 values were determined from 10-point, 1:3 dilution curves starting at either 100 μM or 10 μM with 10 μM ATP, by Reaction...				Bioorg Med Chem Lett 19: 773-7 (2009) BindingDB Entry DOI: 10.7270/Q27D2XFP
					More data for this Ligand-Target Pair
Tyrosine-protein kinase FRK (Homo sapiens (Human))	BDBM50184770 (CHEMBL3823849 | US10294227, Code 112) Show SMILES CN(C)CC1CCN(CCn2nc(-c3ccc(C)cc3)c3c(N)ncnc23)CC1 Show InChI InChI=1S/C22H31N7/c1-16-4-6-18(7-5-16)20-19-21(23)24-15-25-22(19)29(26-20)13-12-28-10-8-17(9-11-28)14-27(2)3/h4-7,15,17H,8-14H2,1-3H3,(H2,23,24,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Compound IC50 values were determined from 10-point, 1:3 dilution curves starting at either 100 μM or 10 μM with 10 μM ATP, by Reaction...				Bioorg Med Chem Lett 19: 773-7 (2009) BindingDB Entry DOI: 10.7270/Q27D2XFP
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Fyn (Homo sapiens (Human))	BDBM50184770 (CHEMBL3823849 | US10294227, Code 112) Show SMILES CN(C)CC1CCN(CCn2nc(-c3ccc(C)cc3)c3c(N)ncnc23)CC1 Show InChI InChI=1S/C22H31N7/c1-16-4-6-18(7-5-16)20-19-21(23)24-15-25-22(19)29(26-20)13-12-28-10-8-17(9-11-28)14-27(2)3/h4-7,15,17H,8-14H2,1-3H3,(H2,23,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Compound IC50 values were determined from 10-point, 1:3 dilution curves starting at either 100 μM or 10 μM with 10 μM ATP, by Reaction...				Bioorg Med Chem Lett 19: 773-7 (2009) BindingDB Entry DOI: 10.7270/Q27D2XFP
					More data for this Ligand-Target Pair
Tyrosine-protein kinase HCK (Homo sapiens (Human))	BDBM50184770 (CHEMBL3823849 | US10294227, Code 112) Show SMILES CN(C)CC1CCN(CCn2nc(-c3ccc(C)cc3)c3c(N)ncnc23)CC1 Show InChI InChI=1S/C22H31N7/c1-16-4-6-18(7-5-16)20-19-21(23)24-15-25-22(19)29(26-20)13-12-28-10-8-17(9-11-28)14-27(2)3/h4-7,15,17H,8-14H2,1-3H3,(H2,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Compound IC50 values were determined from 10-point, 1:3 dilution curves starting at either 100 μM or 10 μM with 10 μM ATP, by Reaction...				Bioorg Med Chem Lett 19: 773-7 (2009) BindingDB Entry DOI: 10.7270/Q27D2XFP
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50184770 (CHEMBL3823849 | US10294227, Code 112) Show SMILES CN(C)CC1CCN(CCn2nc(-c3ccc(C)cc3)c3c(N)ncnc23)CC1 Show InChI InChI=1S/C22H31N7/c1-16-4-6-18(7-5-16)20-19-21(23)24-15-25-22(19)29(26-20)13-12-28-10-8-17(9-11-28)14-27(2)3/h4-7,15,17H,8-14H2,1-3H3,(H2,23,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Compound IC50 values were determined from 10-point, 1:3 dilution curves starting at either 100 μM or 10 μM with 10 μM ATP, by Reaction...				Bioorg Med Chem Lett 19: 773-7 (2009) BindingDB Entry DOI: 10.7270/Q27D2XFP
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50184770 (CHEMBL3823849 | US10294227, Code 112) Show SMILES CN(C)CC1CCN(CCn2nc(-c3ccc(C)cc3)c3c(N)ncnc23)CC1 Show InChI InChI=1S/C22H31N7/c1-16-4-6-18(7-5-16)20-19-21(23)24-15-25-22(19)29(26-20)13-12-28-10-8-17(9-11-28)14-27(2)3/h4-7,15,17H,8-14H2,1-3H3,(H2,23,24,25)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Compound IC50 values were determined from 10-point, 1:3 dilution curves starting at either 100 μM or 10 μM with 10 μM ATP, by Reaction...				Bioorg Med Chem Lett 19: 773-7 (2009) BindingDB Entry DOI: 10.7270/Q27D2XFP
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lyn (Homo sapiens (Human))	BDBM50184770 (CHEMBL3823849 | US10294227, Code 112) Show SMILES CN(C)CC1CCN(CCn2nc(-c3ccc(C)cc3)c3c(N)ncnc23)CC1 Show InChI InChI=1S/C22H31N7/c1-16-4-6-18(7-5-16)20-19-21(23)24-15-25-22(19)29(26-20)13-12-28-10-8-17(9-11-28)14-27(2)3/h4-7,15,17H,8-14H2,1-3H3,(H2,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Compound IC50 values were determined from 10-point, 1:3 dilution curves starting at either 100 μM or 10 μM with 10 μM ATP, by Reaction...				Bioorg Med Chem Lett 19: 773-7 (2009) BindingDB Entry DOI: 10.7270/Q27D2XFP
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM50184770 (CHEMBL3823849 | US10294227, Code 112) Show SMILES CN(C)CC1CCN(CCn2nc(-c3ccc(C)cc3)c3c(N)ncnc23)CC1 Show InChI InChI=1S/C22H31N7/c1-16-4-6-18(7-5-16)20-19-21(23)24-15-25-22(19)29(26-20)13-12-28-10-8-17(9-11-28)14-27(2)3/h4-7,15,17H,8-14H2,1-3H3,(H2,23,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Compound IC50 values were determined from 10-point, 1:3 dilution curves starting at either 100 μM or 10 μM with 10 μM ATP, by Reaction...				Bioorg Med Chem Lett 19: 773-7 (2009) BindingDB Entry DOI: 10.7270/Q27D2XFP
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha (Homo sapiens (Human))	BDBM50184770 (CHEMBL3823849 | US10294227, Code 112) Show SMILES CN(C)CC1CCN(CCn2nc(-c3ccc(C)cc3)c3c(N)ncnc23)CC1 Show InChI InChI=1S/C22H31N7/c1-16-4-6-18(7-5-16)20-19-21(23)24-15-25-22(19)29(26-20)13-12-28-10-8-17(9-11-28)14-27(2)3/h4-7,15,17H,8-14H2,1-3H3,(H2,23,24,25)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Compound IC50 values were determined from 10-point, 1:3 dilution curves starting at either 100 μM or 10 μM with 10 μM ATP, by Reaction...				Bioorg Med Chem Lett 19: 773-7 (2009) BindingDB Entry DOI: 10.7270/Q27D2XFP
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase receptor Ret (Homo sapiens (Human))	BDBM50184770 (CHEMBL3823849 | US10294227, Code 112) Show SMILES CN(C)CC1CCN(CCn2nc(-c3ccc(C)cc3)c3c(N)ncnc23)CC1 Show InChI InChI=1S/C22H31N7/c1-16-4-6-18(7-5-16)20-19-21(23)24-15-25-22(19)29(26-20)13-12-28-10-8-17(9-11-28)14-27(2)3/h4-7,15,17H,8-14H2,1-3H3,(H2,23,24,25)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Compound IC50 values were determined from 10-point, 1:3 dilution curves starting at either 100 μM or 10 μM with 10 μM ATP, by Reaction...				Bioorg Med Chem Lett 19: 773-7 (2009) BindingDB Entry DOI: 10.7270/Q27D2XFP
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50184770 (CHEMBL3823849 | US10294227, Code 112) Show SMILES CN(C)CC1CCN(CCn2nc(-c3ccc(C)cc3)c3c(N)ncnc23)CC1 Show InChI InChI=1S/C22H31N7/c1-16-4-6-18(7-5-16)20-19-21(23)24-15-25-22(19)29(26-20)13-12-28-10-8-17(9-11-28)14-27(2)3/h4-7,15,17H,8-14H2,1-3H3,(H2,23,24,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Compound IC50 values were determined from 10-point, 1:3 dilution curves starting at either 100 μM or 10 μM with 10 μM ATP, by Reaction...				Bioorg Med Chem Lett 19: 773-7 (2009) BindingDB Entry DOI: 10.7270/Q27D2XFP
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha (Homo sapiens (Human))	BDBM50184770 (CHEMBL3823849 | US10294227, Code 112) Show SMILES CN(C)CC1CCN(CCn2nc(-c3ccc(C)cc3)c3c(N)ncnc23)CC1 Show InChI InChI=1S/C22H31N7/c1-16-4-6-18(7-5-16)20-19-21(23)24-15-25-22(19)29(26-20)13-12-28-10-8-17(9-11-28)14-27(2)3/h4-7,15,17H,8-14H2,1-3H3,(H2,23,24,25)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1	n/a	n/a	n/a	n/a	n/a	n/a
University of Edinburgh Curated by ChEMBL					Assay Description Inhibition of human PDGFRalpha using poly[Glu,Tyr]4:1 as substrate in presence of [gamma-33P]ATP				J Med Chem 59: 4697-710 (2016) BindingDB Entry DOI: 10.7270/Q2B85B2D
					More data for this Ligand-Target Pair