BDBM50184797 1-(4-Fluorophenyl)-4-[(1-phenyl-1H-pyrazol-4-yl)methyl]piperazine::1-(4-fluorophenyl)-4-((1-phenyl-1H-pyrazol-4-yl)methyl)piperazine::CHEMBL437490

SMILES: Fc1ccc(cc1)N1CCN(Cc2cnn(c2)-c2ccccc2)CC1

InChI Key: InChIKey=ZQEBKQUIKOLFRO-UHFFFAOYSA-N

Data: 7 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50184797   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50184797 (1-(4-Fluorophenyl)-4-[(1-phenyl-1H-pyrazol-4-yl)me...) Show SMILES Fc1ccc(cc1)N1CCN(Cc2cnn(c2)-c2ccccc2)CC1 Show InChI InChI=1S/C20H21FN4/c21-18-6-8-19(9-7-18)24-12-10-23(11-13-24)15-17-14-22-25(16-17)20-4-2-1-3-5-20/h1-9,14,16H,10-13,15H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human cloned dopamine D4 receptor expressed in CHO cells				Bioorg Med Chem Lett 16: 2955-9 (2006) Article DOI: 10.1016/j.bmcl.2006.02.075 BindingDB Entry DOI: 10.7270/Q21N80QX
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50184797 (1-(4-Fluorophenyl)-4-[(1-phenyl-1H-pyrazol-4-yl)me...) Show SMILES Fc1ccc(cc1)N1CCN(Cc2cnn(c2)-c2ccccc2)CC1 Show InChI InChI=1S/C20H21FN4/c21-18-6-8-19(9-7-18)24-12-10-23(11-13-24)15-17-14-22-25(16-17)20-4-2-1-3-5-20/h1-9,14,16H,10-13,15H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	120	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal do Rio Grande do Sul Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from 5HT1A receptor in Wistar rat hippocampus homogenate				Bioorg Med Chem 18: 1925-35 (2010) Article DOI: 10.1016/j.bmc.2010.01.040 BindingDB Entry DOI: 10.7270/Q2S75H99
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50184797 (1-(4-Fluorophenyl)-4-[(1-phenyl-1H-pyrazol-4-yl)me...) Show SMILES Fc1ccc(cc1)N1CCN(Cc2cnn(c2)-c2ccccc2)CC1 Show InChI InChI=1S/C20H21FN4/c21-18-6-8-19(9-7-18)24-12-10-23(11-13-24)15-17-14-22-25(16-17)20-4-2-1-3-5-20/h1-9,14,16H,10-13,15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human cloned dopamine D2(short) receptor expressed in CHO cells				Bioorg Med Chem Lett 16: 2955-9 (2006) Article DOI: 10.1016/j.bmcl.2006.02.075 BindingDB Entry DOI: 10.7270/Q21N80QX
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50184797 (1-(4-Fluorophenyl)-4-[(1-phenyl-1H-pyrazol-4-yl)me...) Show SMILES Fc1ccc(cc1)N1CCN(Cc2cnn(c2)-c2ccccc2)CC1 Show InChI InChI=1S/C20H21FN4/c21-18-6-8-19(9-7-18)24-12-10-23(11-13-24)15-17-14-22-25(16-17)20-4-2-1-3-5-20/h1-9,14,16H,10-13,15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	450	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human cloned dopamine D2(long) receptor expressed in CHO cells				Bioorg Med Chem Lett 16: 2955-9 (2006) Article DOI: 10.1016/j.bmcl.2006.02.075 BindingDB Entry DOI: 10.7270/Q21N80QX
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50184797 (1-(4-Fluorophenyl)-4-[(1-phenyl-1H-pyrazol-4-yl)me...) Show SMILES Fc1ccc(cc1)N1CCN(Cc2cnn(c2)-c2ccccc2)CC1 Show InChI InChI=1S/C20H21FN4/c21-18-6-8-19(9-7-18)24-12-10-23(11-13-24)15-17-14-22-25(16-17)20-4-2-1-3-5-20/h1-9,14,16H,10-13,15H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	540	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human cloned dopamine D3 receptor expressed in CHO cells				Bioorg Med Chem Lett 16: 2955-9 (2006) Article DOI: 10.1016/j.bmcl.2006.02.075 BindingDB Entry DOI: 10.7270/Q21N80QX
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50184797 (1-(4-Fluorophenyl)-4-[(1-phenyl-1H-pyrazol-4-yl)me...) Show SMILES Fc1ccc(cc1)N1CCN(Cc2cnn(c2)-c2ccccc2)CC1 Show InChI InChI=1S/C20H21FN4/c21-18-6-8-19(9-7-18)24-12-10-23(11-13-24)15-17-14-22-25(16-17)20-4-2-1-3-5-20/h1-9,14,16H,10-13,15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.04E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal do Rio Grande do Sul Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from 5HT2A receptor in Wistar rat cortex homogenate				Bioorg Med Chem 18: 1925-35 (2010) Article DOI: 10.1016/j.bmc.2010.01.040 BindingDB Entry DOI: 10.7270/Q2S75H99
					More data for this Ligand-Target Pair
Dopamine D1 receptor (Sus scrofa)	BDBM50184797 (1-(4-Fluorophenyl)-4-[(1-phenyl-1H-pyrazol-4-yl)me...) Show SMILES Fc1ccc(cc1)N1CCN(Cc2cnn(c2)-c2ccccc2)CC1 Show InChI InChI=1S/C20H21FN4/c21-18-6-8-19(9-7-18)24-12-10-23(11-13-24)15-17-14-22-25(16-17)20-4-2-1-3-5-20/h1-9,14,16H,10-13,15H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]SCH23390 from dopamine D1 receptor in porcine striatal membrane				Bioorg Med Chem Lett 16: 2955-9 (2006) Article DOI: 10.1016/j.bmcl.2006.02.075 BindingDB Entry DOI: 10.7270/Q21N80QX
					More data for this Ligand-Target Pair