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SMILES: CCOC(=O)c1cn2ncnc(Oc3ccc4[nH]ccc4c3)c2c1C(C)C

InChI Key: InChIKey=ITPVQKYFDVJVFO-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50184815   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))		BDBM50184815
PNG
(CHEMBL381973 | ethyl 4-(1H-indol-5-yloxy)-5-isopro...)
Show SMILES CCOC(=O)c1cn2ncnc(Oc3ccc4[nH]ccc4c3)c2c1C(C)C
Show InChI InChI=1S/C20H20N4O3/c1-4-26-20(25)15-10-24-18(17(15)12(2)3)19(22-11-23-24)27-14-5-6-16-13(9-14)7-8-21-16/h5-12,21H,4H2,1-3H3
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Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibitory activity against VEGFR2

J Med Chem 49: 2143-6 (2006)


Article DOI: 10.1021/jm051106d
BindingDB Entry DOI: 10.7270/Q2WW7H7N
More data for this
Ligand-Target Pair