BindingDB logo
myBDB logout

null

SMILES: COC(=O)c1cc2c(Oc3ccc4[nH]ccc4c3)ncnn2c1

InChI Key: InChIKey=JESDZVSHYKKMCA-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50184819   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))		BDBM50184819
PNG
(CHEMBL381104 | methyl 4-(1H-indol-5-yloxy)pyrrolo[...)
Show SMILES COC(=O)c1cc2c(Oc3ccc4[nH]ccc4c3)ncnn2c1
Show InChI InChI=1S/C16H12N4O3/c1-22-16(21)11-7-14-15(18-9-19-20(14)8-11)23-12-2-3-13-10(6-12)4-5-17-13/h2-9,17H,1H3
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 210n/an/an/an/an/an/a



Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibitory activity against VEGFR2

J Med Chem 49: 2143-6 (2006)


Article DOI: 10.1021/jm051106d
BindingDB Entry DOI: 10.7270/Q2WW7H7N
More data for this
Ligand-Target Pair