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SMILES: COC(=O)c1cn2ncnc(Oc3ccc4[nH]c(C)cc4c3)c2c1C

InChI Key: InChIKey=GUDPPZNLSBORFZ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50184820   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))		BDBM50184820
PNG
(CHEMBL205283 | methyl 5-methyl-4-(2-methyl-1H-indo...)
Show SMILES COC(=O)c1cn2ncnc(Oc3ccc4[nH]c(C)cc4c3)c2c1C
Show InChI InChI=1S/C18H16N4O3/c1-10-6-12-7-13(4-5-15(12)21-10)25-17-16-11(2)14(18(23)24-3)8-22(16)20-9-19-17/h4-9,21H,1-3H3
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n/an/a 78n/an/an/an/an/an/a



Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibitory activity against VEGFR2

J Med Chem 49: 2143-6 (2006)


Article DOI: 10.1021/jm051106d
BindingDB Entry DOI: 10.7270/Q2WW7H7N
More data for this
Ligand-Target Pair