BDBM50184834 Ac-Bth-Thr(PO3H2)-Pip-Nal-Gln-NH2::CHEMBL380685
SMILES: C[C@@H](OP(O)(O)=O)[C@H](NC(=O)[C@H](Cc1csc2ccccc12)NC(C)=O)C(=O)N1CCCC[C@@H]1C(=O)N[C@@H](Cc1ccc2ccccc2c1)C(=O)N[C@@H](CCC(N)=O)C(N)=O
InChI Key: InChIKey=WPZGCIDLTHYADD-YIVWXNOFSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Homo sapiens (Human)) | BDBM50184834 (Ac-Bth-Thr(PO3H2)-Pip-Nal-Gln-NH2 | CHEMBL380685) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 258 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Max Planck Research Unit for Enzymology of Protein Folding Curated by ChEMBL | Assay Description Inhibition of human Pin1 PPIase Activity by protease free PPIase assay | J Med Chem 49: 2147-50 (2006) Article DOI: 10.1021/jm060036n BindingDB Entry DOI: 10.7270/Q2S46RJP | |||||||||||
More data for this Ligand-Target Pair |