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SMILES: Cc1ccc(cc1)-c1cc(ccn1)-c1c[nH]nc1-c1ccccn1

InChI Key: InChIKey=HYWIRHSWNFASLU-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50184875   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
TGF-beta receptor type-1


(Homo sapiens (Human))		BDBM50184875
PNG
(2-[4-methylphenyl]-4-(3-pyridin-2-yl-1H-pyrazol-4-...)
Show SMILES Cc1ccc(cc1)-c1cc(ccn1)-c1c[nH]nc1-c1ccccn1
Show InChI InChI=1S/C20H16N4/c1-14-5-7-15(8-6-14)19-12-16(9-11-22-19)17-13-23-24-20(17)18-4-2-3-10-21-18/h2-13H,1H3,(H,23,24)
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antibodypedia
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PC sid
UniChem

Similars
Article
PubMed
n/an/a 28n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Displacement of rhodamine green fluorescently labeled ATP from recombinant GST-ALK5 by FP assay

J Med Chem 49: 2210-21 (2006)


Article DOI: 10.1021/jm0509905
BindingDB Entry DOI: 10.7270/Q2DV1KPB
More data for this
Ligand-Target Pair