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SMILES: C(CC1CCCCC1)Oc1ccc(cc1)-c1cc(ccn1)-c1c[nH]nc1-c1ccccn1

InChI Key: InChIKey=VEZHTNSQYUPFQJ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50184898   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50184898 (2-(4-(2-cyclohexylethoxy)phenyl)-4-(3-(pyridin-2-y...) Show SMILES C(CC1CCCCC1)Oc1ccc(cc1)-c1cc(ccn1)-c1c[nH]nc1-c1ccccn1 Show InChI InChI=1S/C27H28N4O/c1-2-6-20(7-3-1)14-17-32-23-11-9-21(10-12-23)26-18-22(13-16-29-26)24-19-30-31-27(24)25-8-4-5-15-28-25/h4-5,8-13,15-16,18-20H,1-3,6-7,14,17H2,(H,30,31)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	81	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Displacement of rhodamine green fluorescently labeled ATP from recombinant GST-ALK5 by FP assay				J Med Chem 49: 2210-21 (2006) Article DOI: 10.1021/jm0509905 BindingDB Entry DOI: 10.7270/Q2DV1KPB
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50184898 (2-(4-(2-cyclohexylethoxy)phenyl)-4-(3-(pyridin-2-y...) Show SMILES C(CC1CCCCC1)Oc1ccc(cc1)-c1cc(ccn1)-c1c[nH]nc1-c1ccccn1 Show InChI InChI=1S/C27H28N4O/c1-2-6-20(7-3-1)14-17-32-23-11-9-21(10-12-23)26-18-22(13-16-29-26)24-19-30-31-27(24)25-8-4-5-15-28-25/h4-5,8-13,15-16,18-20H,1-3,6-7,14,17H2,(H,30,31)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	81	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of TGFR1				Eur J Med Chem 44: 4259-65 (2009) Article DOI: 10.1016/j.ejmech.2009.07.008 BindingDB Entry DOI: 10.7270/Q2BC3ZM9
					More data for this Ligand-Target Pair