Found 4 hits for monomerid = 50185186 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50185186
(2-(1H-indazol-3-yl)-5-(3-(pyrrolidin-1-yl)propoxy)...)Show SMILES C(COc1ccc2nc([nH]c2c1)-c1n[nH]c2ccccc12)CN1CCCC1 Show InChI InChI=1S/C21H23N5O/c1-2-7-17-16(6-1)20(25-24-17)21-22-18-9-8-15(14-19(18)23-21)27-13-5-12-26-10-3-4-11-26/h1-2,6-9,14H,3-5,10-13H2,(H,22,23)(H,24,25) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 48 | n/a | n/a | n/a | n/a | n/a | n/a |
Chiron Corporation
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR1 |
Bioorg Med Chem Lett 16: 3595-9 (2006)
Article DOI: 10.1016/j.bmcl.2006.03.069
BindingDB Entry DOI: 10.7270/Q2BZ65N7 |
More data for this
Ligand-Target Pair | |
Fibroblast growth factor receptor 1
(Homo sapiens (Human)) | BDBM50185186
(2-(1H-indazol-3-yl)-5-(3-(pyrrolidin-1-yl)propoxy)...)Show SMILES C(COc1ccc2nc([nH]c2c1)-c1n[nH]c2ccccc12)CN1CCCC1 Show InChI InChI=1S/C21H23N5O/c1-2-7-17-16(6-1)20(25-24-17)21-22-18-9-8-15(14-19(18)23-21)27-13-5-12-26-10-3-4-11-26/h1-2,6-9,14H,3-5,10-13H2,(H,22,23)(H,24,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 98 | n/a | n/a | n/a | n/a | n/a | n/a |
Chiron Corporation
Curated by ChEMBL
| Assay Description
Inhibition of FGFR1 |
Bioorg Med Chem Lett 16: 3595-9 (2006)
Article DOI: 10.1016/j.bmcl.2006.03.069
BindingDB Entry DOI: 10.7270/Q2BZ65N7 |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Mus musculus) | BDBM50185186
(2-(1H-indazol-3-yl)-5-(3-(pyrrolidin-1-yl)propoxy)...)Show SMILES C(COc1ccc2nc([nH]c2c1)-c1n[nH]c2ccccc12)CN1CCCC1 Show InChI InChI=1S/C21H23N5O/c1-2-7-17-16(6-1)20(25-24-17)21-22-18-9-8-15(14-19(18)23-21)27-13-5-12-26-10-3-4-11-26/h1-2,6-9,14H,3-5,10-13H2,(H,22,23)(H,24,25) | PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 170 | n/a | n/a | n/a | n/a | n/a | n/a |
Chiron Corporation
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 |
Bioorg Med Chem Lett 16: 3595-9 (2006)
Article DOI: 10.1016/j.bmcl.2006.03.069
BindingDB Entry DOI: 10.7270/Q2BZ65N7 |
More data for this
Ligand-Target Pair | |
Platelet-derived growth factor receptor beta
(Mus musculus (mouse)) | BDBM50185186
(2-(1H-indazol-3-yl)-5-(3-(pyrrolidin-1-yl)propoxy)...)Show SMILES C(COc1ccc2nc([nH]c2c1)-c1n[nH]c2ccccc12)CN1CCCC1 Show InChI InChI=1S/C21H23N5O/c1-2-7-17-16(6-1)20(25-24-17)21-22-18-9-8-15(14-19(18)23-21)27-13-5-12-26-10-3-4-11-26/h1-2,6-9,14H,3-5,10-13H2,(H,22,23)(H,24,25) | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 440 | n/a | n/a | n/a | n/a | n/a | n/a |
Chiron Corporation
Curated by ChEMBL
| Assay Description
Inhibition of PDGFRbeta |
Bioorg Med Chem Lett 16: 3595-9 (2006)
Article DOI: 10.1016/j.bmcl.2006.03.069
BindingDB Entry DOI: 10.7270/Q2BZ65N7 |
More data for this
Ligand-Target Pair | |
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