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SMILES: [#6]-1-[#6]-c2ccccc2\[#6](=[#6]/c2ccccc2)-c2ccccc-12

InChI Key: InChIKey=VANWUZCCKGBSMP-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50185243   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50185243
PNG
(5-benzylidene-10,11-dihydro-5H-dibenzo[a,d]cyclohe...)
Show SMILES [#6]-1-[#6]-c2ccccc2\[#6](=[#6]/c2ccccc2)-c2ccccc-12
Show InChI InChI=1S/C22H18/c1-2-8-17(9-3-1)16-22-20-12-6-4-10-18(20)14-15-19-11-5-7-13-21(19)22/h1-13,16H,14-15H2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
>100n/an/an/an/an/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]-dexamethasone from human glucocorticoid receptor expressed in HEK293 cells


J Med Chem 57: 849-60 (2014)


Article DOI: 10.1021/jm401616g
BindingDB Entry DOI: 10.7270/Q23X885F
More data for this
Ligand-Target Pair
Cytochrome P450 2D6


(Homo sapiens (Human))
BDBM50185243
PNG
(5-benzylidene-10,11-dihydro-5H-dibenzo[a,d]cyclohe...)
Show SMILES [#6]-1-[#6]-c2ccccc2\[#6](=[#6]/c2ccccc2)-c2ccccc-12
Show InChI InChI=1S/C22H18/c1-2-8-17(9-3-1)16-22-20-12-6-4-10-18(20)14-15-19-11-5-7-13-21(19)22/h1-13,16H,14-15H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a>2.00E+5n/an/an/an/an/an/a



Vrije Universiteit

Curated by ChEMBL


Assay Description
Inhibition of human CYP2D6 expressed in Escherichia coli JM109


J Med Chem 49: 2417-30 (2006)


Article DOI: 10.1021/jm0508538
BindingDB Entry DOI: 10.7270/Q2930TZX
More data for this
Ligand-Target Pair