BDBM50185256 2-(5H-dibenzo[a,d]cyclohepten-5-yl)-3-hydroxy-indan-1-one::CHEMBL377088::GBR-30111

SMILES: OC1C(C2c3ccccc3C=Cc3ccccc23)C(=O)c2ccccc12

InChI Key: InChIKey=IPZYFGSKGGEOJV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50185256   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 2D6 (Homo sapiens (Human))	BDBM50185256 (2-(5H-dibenzo[a,d]cyclohepten-5-yl)-3-hydroxy-inda...) Show SMILES OC1C(C2c3ccccc3C=Cc3ccccc23)C(=O)c2ccccc12 |c:11| Show InChI InChI=1S/C24H18O2/c25-23-19-11-5-6-12-20(19)24(26)22(23)21-17-9-3-1-7-15(17)13-14-16-8-2-4-10-18(16)21/h1-14,21-23,25H	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vrije Universiteit Curated by ChEMBL					Assay Description Inhibition of human CYP2D6 expressed in Escherichia coli JM109				J Med Chem 49: 2417-30 (2006) Article DOI: 10.1021/jm0508538 BindingDB Entry DOI: 10.7270/Q2930TZX
					More data for this Ligand-Target Pair