BDBM50185473 4-(3-(4-chlorophenyl)-3-hydroxy-8-aza-bicyclo[3.2.1]octan-8-yl)-1-(4-fluorophenyl)butan-1-one::4-[3-(4-Chloro-phenyl)-3-hydroxy-8-aza-bicyclo[3.2.1]oct-8-yl]-1-(4-fluoro-phenyl)-butan-1-one::4-[3-(4-Chlorophenyl)-3-hydroxy-8-azabicyclo[3.2.1]oct-8-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL210578
SMILES: OC1(CC2CCC(C1)N2CCCC(=O)c1ccc(F)cc1)c1ccc(Cl)cc1
InChI Key: InChIKey=CXQUOFVDYCOSEZ-UHFFFAOYSA-N
Data: 35 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50185473 (4-(3-(4-chlorophenyl)-3-hydroxy-8-aza-bicyclo[3.2....) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 0.309 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A & M University Curated by ChEMBL | Assay Description Cataleptogenic effect against cloned human Dopamine receptor D2 in male Sprague-Dawley rats in a bar test | Bioorg Med Chem Lett 13: 3779-82 (2003) BindingDB Entry DOI: 10.7270/Q2BK1BQH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50185473 (4-(3-(4-chlorophenyl)-3-hydroxy-8-aza-bicyclo[3.2....) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 0.310 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A & M University Curated by ChEMBL | Assay Description In vitro ability to inhibit the binding of [3H]-spiperone to cloned human Dopamine receptor D2 using apomorphine induced climbing test in male Swiss ... | Bioorg Med Chem Lett 13: 3779-82 (2003) BindingDB Entry DOI: 10.7270/Q2BK1BQH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50185473 (4-(3-(4-chlorophenyl)-3-hydroxy-8-aza-bicyclo[3.2....) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 0.310 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A&M University Curated by ChEMBL | Assay Description Displacement of [3H]N-methylspiperone from human dopamine D2 receptor by liquid scintillation counting | Bioorg Med Chem Lett 24: 4294-7 (2014) Article DOI: 10.1016/j.bmcl.2014.07.018 BindingDB Entry DOI: 10.7270/Q2222WF8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(3) dopamine receptor (Homo sapiens (Human)) | BDBM50185473 (4-(3-(4-chlorophenyl)-3-hydroxy-8-aza-bicyclo[3.2....) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 0.708 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A & M University Curated by ChEMBL | Assay Description Cataleptogenic effect against cloned human Dopamine receptor D3 in male Sprague-Dawley rats in a bar test | Bioorg Med Chem Lett 13: 3779-82 (2003) BindingDB Entry DOI: 10.7270/Q2BK1BQH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(3) dopamine receptor (Homo sapiens (Human)) | BDBM50185473 (4-(3-(4-chlorophenyl)-3-hydroxy-8-aza-bicyclo[3.2....) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 0.710 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A & M University Curated by ChEMBL | Assay Description In vitro ability to inhibit the binding of [3H]-7-OH-DPAT to cloned human Dopamine receptor D3 using apomorphine induced climbing test in male Swiss ... | Bioorg Med Chem Lett 13: 3779-82 (2003) BindingDB Entry DOI: 10.7270/Q2BK1BQH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(3) dopamine receptor (Homo sapiens (Human)) | BDBM50185473 (4-(3-(4-chlorophenyl)-3-hydroxy-8-aza-bicyclo[3.2....) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 0.710 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A&M University Curated by ChEMBL | Assay Description Displacement of [3H]N-methylspiperone from human dopamine D3 receptor by liquid scintillation counting | Bioorg Med Chem Lett 24: 4294-7 (2014) Article DOI: 10.1016/j.bmcl.2014.07.018 BindingDB Entry DOI: 10.7270/Q2222WF8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50185473 (4-(3-(4-chlorophenyl)-3-hydroxy-8-aza-bicyclo[3.2....) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A& M University Curated by ChEMBL | Assay Description Binding affinity to human cloned dopamine D2 receptor by radioligand binding assay | Bioorg Med Chem Lett 16: 3219-23 (2006) Article DOI: 10.1016/j.bmcl.2006.03.057 BindingDB Entry DOI: 10.7270/Q2571BM5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50185473 (4-(3-(4-chlorophenyl)-3-hydroxy-8-aza-bicyclo[3.2....) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A&M University Curated by ChEMBL | Assay Description Binding affinity to human cloned dopamine D2 receptor | Bioorg Med Chem 16: 7291-301 (2008) Article DOI: 10.1016/j.bmc.2008.06.030 BindingDB Entry DOI: 10.7270/Q2ZP45XW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50185473 (4-(3-(4-chlorophenyl)-3-hydroxy-8-aza-bicyclo[3.2....) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A&M University Curated by ChEMBL | Assay Description Displacement of [3H]N-methylspiperone from human dopamine D2 receptor by liquid scintillation counting | Bioorg Med Chem 17: 1716-23 (2009) Article DOI: 10.1016/j.bmc.2008.12.054 BindingDB Entry DOI: 10.7270/Q2NG4QGT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(3) dopamine receptor (Homo sapiens (Human)) | BDBM50185473 (4-(3-(4-chlorophenyl)-3-hydroxy-8-aza-bicyclo[3.2....) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 5.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A&M University Curated by ChEMBL | Assay Description Displacement of [3H]N-methylspiperone from human dopamine D3 receptor by liquid scintillation counting | Bioorg Med Chem 17: 1716-23 (2009) Article DOI: 10.1016/j.bmc.2008.12.054 BindingDB Entry DOI: 10.7270/Q2NG4QGT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(3) dopamine receptor (Homo sapiens (Human)) | BDBM50185473 (4-(3-(4-chlorophenyl)-3-hydroxy-8-aza-bicyclo[3.2....) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 5.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A&M University Curated by ChEMBL | Assay Description Binding affinity to dopamine D3 receptor (unknown origin) | Bioorg Med Chem 24: 3671-9 (2016) BindingDB Entry DOI: 10.7270/Q2W66NPV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(3) dopamine receptor (Homo sapiens (Human)) | BDBM50185473 (4-(3-(4-chlorophenyl)-3-hydroxy-8-aza-bicyclo[3.2....) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 5.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A& M University Curated by ChEMBL | Assay Description Binding affinity to human cloned dopamine D3 receptor by radioligand binding assay | Bioorg Med Chem Lett 16: 3219-23 (2006) Article DOI: 10.1016/j.bmcl.2006.03.057 BindingDB Entry DOI: 10.7270/Q2571BM5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(4) dopamine receptor (Homo sapiens (Human)) | BDBM50185473 (4-(3-(4-chlorophenyl)-3-hydroxy-8-aza-bicyclo[3.2....) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 5.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A&M University Curated by ChEMBL | Assay Description Displacement of [125I]DOI from human dopamine D4 receptor by liquid scintillation counting | Bioorg Med Chem 17: 1716-23 (2009) Article DOI: 10.1016/j.bmc.2008.12.054 BindingDB Entry DOI: 10.7270/Q2NG4QGT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(4) dopamine receptor (Homo sapiens (Human)) | BDBM50185473 (4-(3-(4-chlorophenyl)-3-hydroxy-8-aza-bicyclo[3.2....) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 5.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A&M University Curated by ChEMBL | Assay Description Binding affinity to human cloned dopamine D4 receptor | Bioorg Med Chem 16: 7291-301 (2008) Article DOI: 10.1016/j.bmc.2008.06.030 BindingDB Entry DOI: 10.7270/Q2ZP45XW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(4) dopamine receptor (Homo sapiens (Human)) | BDBM50185473 (4-(3-(4-chlorophenyl)-3-hydroxy-8-aza-bicyclo[3.2....) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 5.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A& M University Curated by ChEMBL | Assay Description Binding affinity to human cloned dopamine D4.4 receptor by radioligand binding assay | Bioorg Med Chem Lett 16: 3219-23 (2006) Article DOI: 10.1016/j.bmcl.2006.03.057 BindingDB Entry DOI: 10.7270/Q2571BM5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dopamine receptor (RAT) | BDBM50185473 (4-(3-(4-chlorophenyl)-3-hydroxy-8-aza-bicyclo[3.2....) | Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A&M University Curated by ChEMBL | Assay Description Displacement of [3H]N-methylspiperone from rat dopamine D4 receptor by liquid scintillation counting | Bioorg Med Chem Lett 24: 4294-7 (2014) Article DOI: 10.1016/j.bmcl.2014.07.018 BindingDB Entry DOI: 10.7270/Q2222WF8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(4) dopamine receptor (Homo sapiens (Human)) | BDBM50185473 (4-(3-(4-chlorophenyl)-3-hydroxy-8-aza-bicyclo[3.2....) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A & M University Curated by ChEMBL | Assay Description In vitro ability to inhibit the binding of [3H]-spiperone to cloned human dopamine receptor D4 using apomorphine induced climbing test in male Swiss ... | Bioorg Med Chem Lett 13: 3779-82 (2003) BindingDB Entry DOI: 10.7270/Q2BK1BQH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(4) dopamine receptor (Homo sapiens (Human)) | BDBM50185473 (4-(3-(4-chlorophenyl)-3-hydroxy-8-aza-bicyclo[3.2....) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A & M University Curated by ChEMBL | Assay Description Cataleptogenic effect against cloned human dopamine receptor D4 in male Sprague-Dawley rats in a bar test | Bioorg Med Chem Lett 13: 3779-82 (2003) BindingDB Entry DOI: 10.7270/Q2BK1BQH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50185473 (4-(3-(4-chlorophenyl)-3-hydroxy-8-aza-bicyclo[3.2....) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 27.7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A&M University Curated by ChEMBL | Assay Description Binding affinity to human cloned 5HT1A receptor | Bioorg Med Chem 16: 7291-301 (2008) Article DOI: 10.1016/j.bmc.2008.06.030 BindingDB Entry DOI: 10.7270/Q2ZP45XW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50185473 (4-(3-(4-chlorophenyl)-3-hydroxy-8-aza-bicyclo[3.2....) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 28 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A& M University Curated by ChEMBL | Assay Description Binding affinity to human cloned 5HT1A receptor by radioligand binding assay | Bioorg Med Chem Lett 16: 3219-23 (2006) Article DOI: 10.1016/j.bmcl.2006.03.057 BindingDB Entry DOI: 10.7270/Q2571BM5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50185473 (4-(3-(4-chlorophenyl)-3-hydroxy-8-aza-bicyclo[3.2....) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 28 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A&M University Curated by ChEMBL | Assay Description Displacement of [3H] 8-OH-DPAT from human 5-HT1A receptor by liquid scintillation counting | Bioorg Med Chem Lett 24: 4294-7 (2014) Article DOI: 10.1016/j.bmcl.2014.07.018 BindingDB Entry DOI: 10.7270/Q2222WF8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Homo sapiens (Human)) | BDBM50185473 (4-(3-(4-chlorophenyl)-3-hydroxy-8-aza-bicyclo[3.2....) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 30.9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A&M University Curated by ChEMBL | Assay Description Binding affinity to human cloned 5HT2A receptor | Bioorg Med Chem 16: 7291-301 (2008) Article DOI: 10.1016/j.bmc.2008.06.030 BindingDB Entry DOI: 10.7270/Q2ZP45XW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Homo sapiens (Human)) | BDBM50185473 (4-(3-(4-chlorophenyl)-3-hydroxy-8-aza-bicyclo[3.2....) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 31 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A&M University Curated by ChEMBL | Assay Description Displacement of [3H]Ketanserin from human 5-HT2A receptor by liquid scintillation counting | Bioorg Med Chem Lett 24: 4294-7 (2014) Article DOI: 10.1016/j.bmcl.2014.07.018 BindingDB Entry DOI: 10.7270/Q2222WF8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Homo sapiens (Human)) | BDBM50185473 (4-(3-(4-chlorophenyl)-3-hydroxy-8-aza-bicyclo[3.2....) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 31 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A& M University Curated by ChEMBL | Assay Description Binding affinity to human cloned 5HT2A receptor by radioligand binding assay | Bioorg Med Chem Lett 16: 3219-23 (2006) Article DOI: 10.1016/j.bmcl.2006.03.057 BindingDB Entry DOI: 10.7270/Q2571BM5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1A adrenergic receptor (Homo sapiens (Human)) | BDBM50185473 (4-(3-(4-chlorophenyl)-3-hydroxy-8-aza-bicyclo[3.2....) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 39 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A& M University Curated by ChEMBL | Assay Description Binding affinity to human cloned adrenergic alpha-1A receptor by radioligand binding assay | Bioorg Med Chem Lett 16: 3219-23 (2006) Article DOI: 10.1016/j.bmcl.2006.03.057 BindingDB Entry DOI: 10.7270/Q2571BM5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adrenergic alpha1B (Homo sapiens (Human)) | BDBM50185473 (4-(3-(4-chlorophenyl)-3-hydroxy-8-aza-bicyclo[3.2....) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 43 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A& M University Curated by ChEMBL | Assay Description Binding affinity to human cloned adrenergic alpha-1B receptor by radioligand binding assay | Bioorg Med Chem Lett 16: 3219-23 (2006) Article DOI: 10.1016/j.bmcl.2006.03.057 BindingDB Entry DOI: 10.7270/Q2571BM5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2C adrenergic receptor (Homo sapiens (Human)) | BDBM50185473 (4-(3-(4-chlorophenyl)-3-hydroxy-8-aza-bicyclo[3.2....) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 143 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A& M University Curated by ChEMBL | Assay Description Binding affinity to human cloned adrenergic alpha-2C receptor by radioligand binding assay | Bioorg Med Chem Lett 16: 3219-23 (2006) Article DOI: 10.1016/j.bmcl.2006.03.057 BindingDB Entry DOI: 10.7270/Q2571BM5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2B adrenergic receptor (Homo sapiens (Human)) | BDBM50185473 (4-(3-(4-chlorophenyl)-3-hydroxy-8-aza-bicyclo[3.2....) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 516 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A& M University Curated by ChEMBL | Assay Description Binding affinity to human cloned adrenergic alpha-2B receptor by radioligand binding assay | Bioorg Med Chem Lett 16: 3219-23 (2006) Article DOI: 10.1016/j.bmcl.2006.03.057 BindingDB Entry DOI: 10.7270/Q2571BM5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50185473 (4-(3-(4-chlorophenyl)-3-hydroxy-8-aza-bicyclo[3.2....) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 872 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A& M University Curated by ChEMBL | Assay Description Binding affinity to human cloned 5HT2C receptor by radioligand binding assay | Bioorg Med Chem Lett 16: 3219-23 (2006) Article DOI: 10.1016/j.bmcl.2006.03.057 BindingDB Entry DOI: 10.7270/Q2571BM5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin receptor 2a and 2c (5HT2A and 5HT2C) (Rattus norvegicus (Rat)) | BDBM50185473 (4-(3-(4-chlorophenyl)-3-hydroxy-8-aza-bicyclo[3.2....) | KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 872 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A&M University Curated by ChEMBL | Assay Description Displacement of [3H]Mesulergine from rat 5-HT2C receptor by liquid scintillation counting | Bioorg Med Chem Lett 24: 4294-7 (2014) Article DOI: 10.1016/j.bmcl.2014.07.018 BindingDB Entry DOI: 10.7270/Q2222WF8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50185473 (4-(3-(4-chlorophenyl)-3-hydroxy-8-aza-bicyclo[3.2....) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 872 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A&M University Curated by ChEMBL | Assay Description Binding affinity to human cloned 5HT2C receptor | Bioorg Med Chem 16: 7291-301 (2008) Article DOI: 10.1016/j.bmc.2008.06.030 BindingDB Entry DOI: 10.7270/Q2ZP45XW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2A adrenergic receptor (Homo sapiens (Human)) | BDBM50185473 (4-(3-(4-chlorophenyl)-3-hydroxy-8-aza-bicyclo[3.2....) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 2.84E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A& M University Curated by ChEMBL | Assay Description Binding affinity to human cloned adrenergic alpha-2A receptor by radioligand binding assay | Bioorg Med Chem Lett 16: 3219-23 (2006) Article DOI: 10.1016/j.bmcl.2006.03.057 BindingDB Entry DOI: 10.7270/Q2571BM5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H1 receptor (Homo sapiens (Human)) | BDBM50185473 (4-(3-(4-chlorophenyl)-3-hydroxy-8-aza-bicyclo[3.2....) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 8.78E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A&M University Curated by ChEMBL | Assay Description Displacement of [3H]Pyrilamine from human histamine H1 receptor by liquid scintillation counting | Bioorg Med Chem Lett 24: 4294-7 (2014) Article DOI: 10.1016/j.bmcl.2014.07.018 BindingDB Entry DOI: 10.7270/Q2222WF8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H1 receptor (Homo sapiens (Human)) | BDBM50185473 (4-(3-(4-chlorophenyl)-3-hydroxy-8-aza-bicyclo[3.2....) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 8.78E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A& M University Curated by ChEMBL | Assay Description Binding affinity to human cloned histamine H1 receptor by radioligand binding assay | Bioorg Med Chem Lett 16: 3219-23 (2006) Article DOI: 10.1016/j.bmcl.2006.03.057 BindingDB Entry DOI: 10.7270/Q2571BM5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H1 receptor (Homo sapiens (Human)) | BDBM50185473 (4-(3-(4-chlorophenyl)-3-hydroxy-8-aza-bicyclo[3.2....) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 8.78E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A&M University Curated by ChEMBL | Assay Description Binding affinity to human cloned histamine H1 receptor | Bioorg Med Chem 16: 7291-301 (2008) Article DOI: 10.1016/j.bmc.2008.06.030 BindingDB Entry DOI: 10.7270/Q2ZP45XW | |||||||||||
More data for this Ligand-Target Pair |