BDBM50185515 7-(2,5-difluorophenyl)-3-(2-fluorophenyl)-2-((2-methyl-2H-1,2,4-triazol-3-yl)methoxy)pyrazolo[1,5-d][1,2,4]triazine::CHEMBL212273

SMILES: Cn1ncnc1COc1nn2c(nncc2c1-c1ccccc1F)-c1cc(F)ccc1F

InChI Key: InChIKey=SGQQJEBYGVTMRA-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50185515   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GABA receptor alpha-3/beta-3/gamma-2 subunit (Homo sapiens (Human))	BDBM50185515 (7-(2,5-difluorophenyl)-3-(2-fluorophenyl)-2-((2-me...) Show SMILES Cn1ncnc1COc1nn2c(nncc2c1-c1ccccc1F)-c1cc(F)ccc1F |(38.27,-47.4,;36.75,-47.17,;35.67,-48.28,;34.29,-47.6,;34.51,-46.07,;36.03,-45.8,;36.81,-44.47,;36.04,-43.14,;36.82,-41.81,;38.36,-41.65,;38.68,-40.14,;40.02,-39.37,;40.02,-37.82,;38.68,-37.06,;37.35,-37.83,;37.35,-39.37,;36.2,-40.39,;34.86,-39.63,;34.87,-38.09,;33.53,-37.33,;32.2,-38.1,;32.21,-39.65,;33.54,-40.41,;33.56,-41.95,;41.36,-40.14,;41.36,-41.68,;42.69,-42.45,;42.69,-43.99,;44.02,-41.68,;44.02,-40.13,;42.68,-39.37,;42.68,-37.83,)| Show InChI InChI=1S/C21H14F3N7O/c1-30-18(25-11-27-30)10-32-21-19(13-4-2-3-5-15(13)23)17-9-26-28-20(31(17)29-21)14-8-12(22)6-7-16(14)24/h2-9,11H,10H2,1H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]Ro15-1788 binding to human recombinant GABA-Aalpha3 plus beta3gamma2 receptor expressed in L(tk-) cells				Bioorg Med Chem Lett 16: 3550-4 (2006) Article DOI: 10.1016/j.bmcl.2006.03.081 BindingDB Entry DOI: 10.7270/Q21J99CH
					More data for this Ligand-Target Pair