BDBM50185518 3-(2-fluorophenyl)-7-(furan-3-yl)-2-((2-methyl-2H-1,2,4-triazol-3-yl)methoxy)pyrazolo[1,5-d][1,2,4]triazine::CHEMBL208940

SMILES: Cn1ncnc1COc1nn2c(nncc2c1-c1ccccc1F)-c1ccoc1

InChI Key: InChIKey=LYZCPNJIFQNJQM-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50185518   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GABA receptor alpha-3/beta-3/gamma-2 subunit (Homo sapiens (Human))	BDBM50185518 (3-(2-fluorophenyl)-7-(furan-3-yl)-2-((2-methyl-2H-...) Show SMILES Cn1ncnc1COc1nn2c(nncc2c1-c1ccccc1F)-c1ccoc1 |(-5.29,-32.68,;-6.81,-32.45,;-7.88,-33.56,;-9.27,-32.88,;-9.05,-31.35,;-7.52,-31.09,;-6.75,-29.76,;-7.51,-28.42,;-6.74,-27.09,;-5.2,-26.93,;-4.88,-25.42,;-3.53,-24.65,;-3.54,-23.1,;-4.88,-22.34,;-6.21,-23.11,;-6.21,-24.65,;-7.36,-25.68,;-8.7,-24.91,;-8.69,-23.38,;-10.03,-22.61,;-11.36,-23.39,;-11.35,-24.93,;-10.01,-25.69,;-10,-27.23,;-2.2,-25.42,;-2.15,-26.95,;-.67,-27.38,;.2,-26.11,;-.75,-24.89,)| Show InChI InChI=1S/C19H14FN7O2/c1-26-16(21-11-23-26)10-29-19-17(13-4-2-3-5-14(13)20)15-8-22-24-18(27(15)25-19)12-6-7-28-9-12/h2-9,11H,10H2,1H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.610	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]Ro15-1788 binding to human recombinant GABA-Aalpha3 plus beta3gamma2 receptor expressed in L(tk-) cells				Bioorg Med Chem Lett 16: 3550-4 (2006) Article DOI: 10.1016/j.bmcl.2006.03.081 BindingDB Entry DOI: 10.7270/Q21J99CH
					More data for this Ligand-Target Pair