BDBM50185719 (R)-1-(3-aminophenyl)-4-(3-(cyclopentyloxy)-4-methoxyphenyl)pyrrolidin-2-one::CHEMBL379813

SMILES: COc1ccc(cc1OC1CCCC1)[C@@H]1CN(C(=O)C1)c1cccc(N)c1

InChI Key: InChIKey=MBLZDHJUHFQZLN-INIZCTEOSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50185719   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1)	BDBM50185719 ((R)-1-(3-aminophenyl)-4-(3-(cyclopentyloxy)-4-meth...) Show SMILES COc1ccc(cc1OC1CCCC1)[C@@H]1CN(C(=O)C1)c1cccc(N)c1 Show InChI InChI=1S/C22H26N2O3/c1-26-20-10-9-15(11-21(20)27-19-7-2-3-8-19)16-12-22(25)24(14-16)18-6-4-5-17(23)13-18/h4-6,9-11,13,16,19H,2-3,7-8,12,14,23H2,1H3/t16-/m0/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Genomics Institute of the Novartis Research Foundation Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase				Bioorg Med Chem Lett 16: 3430-3 (2006) Article DOI: 10.1016/j.bmcl.2006.04.012 BindingDB Entry DOI: 10.7270/Q270827S
					More data for this Ligand-Target Pair