BDBM50185753 CHEMBL3822702
SMILES: CC(C)c1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(N)=O
InChI Key: InChIKey=DUCKWYWYGJQFPA-FKWFRFQNSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Mu-type opioid receptor (Rattus norvegicus (rat)) | BDBM50185753 (CHEMBL3822702) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 4.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing Medical University Curated by ChEMBL | Assay Description Displacement of [3H]DAMGO from mu-type opioid receptor in rat brain membranes incubated for 2 hrs | Bioorg Med Chem Lett 26: 3629-31 (2016) BindingDB Entry DOI: 10.7270/Q2ZW1NVQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig)) | BDBM50185753 (CHEMBL3822702) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 472 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing Medical University Curated by ChEMBL | Assay Description Displacement of [3H]U69,593 from kappa-type opioid receptor in guniea pig brain membranes incubated for 2 hrs | Bioorg Med Chem Lett 26: 3629-31 (2016) BindingDB Entry DOI: 10.7270/Q2ZW1NVQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor (Rattus norvegicus (rat)) | BDBM50185753 (CHEMBL3822702) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 4.67E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing Medical University Curated by ChEMBL | Assay Description Displacement of [3H]DSLET from delta-type opioid receptor in rat brain membranes incubated for 2 hrs | Bioorg Med Chem Lett 26: 3629-31 (2016) BindingDB Entry DOI: 10.7270/Q2ZW1NVQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (GUINEA PIG) | BDBM50185753 (CHEMBL3822702) | UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 410 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing Medical University Curated by ChEMBL | Assay Description Agonist activity at mu opioid receptor in guinea pig ileum assessed as inhibition of electrically-stimulated muscle contraction | Bioorg Med Chem Lett 26: 3629-31 (2016) BindingDB Entry DOI: 10.7270/Q2ZW1NVQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor (MOUSE) | BDBM50185753 (CHEMBL3822702) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 7.17E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing Medical University Curated by ChEMBL | Assay Description Agonist activity at delta opioid receptor in albino mouse vas deferens assessed as inhibition of electrically-stimulated muscle contraction | Bioorg Med Chem Lett 26: 3629-31 (2016) BindingDB Entry DOI: 10.7270/Q2ZW1NVQ | |||||||||||
More data for this Ligand-Target Pair |