Found 4 hits for monomerid = 50185775 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50185775
(7-(1-(2,4-difluorophenethyl)piperazine-4-carbonyl)...)Show SMILES Fc1ccc(CCN2CCN(CC2)C(=O)c2cccc3c(c[nH]c23)C#N)c(F)c1 Show InChI InChI=1S/C22H20F2N4O/c23-17-5-4-15(20(24)12-17)6-7-27-8-10-28(11-9-27)22(29)19-3-1-2-18-16(13-25)14-26-21(18)19/h1-5,12,14,26H,6-11H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 0.870 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme
Curated by ChEMBL
| Assay Description Binding affinity to human 5HT2A |
Bioorg Med Chem Lett 16: 3201-4 (2006)
Article DOI: 10.1016/j.bmcl.2006.03.050 BindingDB Entry DOI: 10.7270/Q20K2867 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human)) | BDBM50185775
(7-(1-(2,4-difluorophenethyl)piperazine-4-carbonyl)...)Show SMILES Fc1ccc(CCN2CCN(CC2)C(=O)c2cccc3c(c[nH]c23)C#N)c(F)c1 Show InChI InChI=1S/C22H20F2N4O/c23-17-5-4-15(20(24)12-17)6-7-27-8-10-28(11-9-27)22(29)19-3-1-2-18-16(13-25)14-26-21(18)19/h1-5,12,14,26H,6-11H2 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 557 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme
Curated by ChEMBL
| Assay Description Binding affinity to human 5HT2C |
Bioorg Med Chem Lett 16: 3201-4 (2006)
Article DOI: 10.1016/j.bmcl.2006.03.050 BindingDB Entry DOI: 10.7270/Q20K2867 |
More data for this Ligand-Target Pair | |
D(2) dopamine receptor
(Homo sapiens (Human)) | BDBM50185775
(7-(1-(2,4-difluorophenethyl)piperazine-4-carbonyl)...)Show SMILES Fc1ccc(CCN2CCN(CC2)C(=O)c2cccc3c(c[nH]c23)C#N)c(F)c1 Show InChI InChI=1S/C22H20F2N4O/c23-17-5-4-15(20(24)12-17)6-7-27-8-10-28(11-9-27)22(29)19-3-1-2-18-16(13-25)14-26-21(18)19/h1-5,12,14,26H,6-11H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme
Curated by ChEMBL
| Assay Description Binding affinity to human D2 receptor |
Bioorg Med Chem Lett 16: 3201-4 (2006)
Article DOI: 10.1016/j.bmcl.2006.03.050 BindingDB Entry DOI: 10.7270/Q20K2867 |
More data for this Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50185775
(7-(1-(2,4-difluorophenethyl)piperazine-4-carbonyl)...)Show SMILES Fc1ccc(CCN2CCN(CC2)C(=O)c2cccc3c(c[nH]c23)C#N)c(F)c1 Show InChI InChI=1S/C22H20F2N4O/c23-17-5-4-15(20(24)12-17)6-7-27-8-10-28(11-9-27)22(29)19-3-1-2-18-16(13-25)14-26-21(18)19/h1-5,12,14,26H,6-11H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.27E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme
Curated by ChEMBL
| Assay Description Binding affinity to human IKr |
Bioorg Med Chem Lett 16: 3201-4 (2006)
Article DOI: 10.1016/j.bmcl.2006.03.050 BindingDB Entry DOI: 10.7270/Q20K2867 |
More data for this Ligand-Target Pair | |