null

SMILES: Cc1[nH]c2ccc(Cl)cc2c1C1CCN(CC1)C1Cc2cccc3cccc1c23

InChI Key: InChIKey=OGLIFFKVFKYPEO-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50185796   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nociceptin receptor (Homo sapiens (Human))	BDBM50185796 (5-chloro-3-(1-(1,2-dihydroacenaphthylen-1-yl)piper...) Show SMILES Cc1[nH]c2ccc(Cl)cc2c1C1CCN(CC1)C1Cc2cccc3cccc1c23 Show InChI InChI=1S/C26H25ClN2/c1-16-25(22-15-20(27)8-9-23(22)28-16)18-10-12-29(13-11-18)24-14-19-6-2-4-17-5-3-7-21(24)26(17)19/h2-9,15,18,24,28H,10-14H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Agonist activity at ORL1 receptor expressed in HEK293 cells by calciun flux assay				Bioorg Med Chem Lett 16: 3524-8 (2006) Article DOI: 10.1016/j.bmcl.2006.03.094 BindingDB Entry DOI: 10.7270/Q2VT1RQJ
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50185796 (5-chloro-3-(1-(1,2-dihydroacenaphthylen-1-yl)piper...) Show SMILES Cc1[nH]c2ccc(Cl)cc2c1C1CCN(CC1)C1Cc2cccc3cccc1c23 Show InChI InChI=1S/C26H25ClN2/c1-16-25(22-15-20(27)8-9-23(22)28-16)18-10-12-29(13-11-18)24-14-19-6-2-4-17-5-3-7-21(24)26(17)19/h2-9,15,18,24,28H,10-14H2,1H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	260	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from mu opioid receptor expressed in HEK293 cells				Bioorg Med Chem Lett 16: 3524-8 (2006) Article DOI: 10.1016/j.bmcl.2006.03.094 BindingDB Entry DOI: 10.7270/Q2VT1RQJ
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50185796 (5-chloro-3-(1-(1,2-dihydroacenaphthylen-1-yl)piper...) Show SMILES Cc1[nH]c2ccc(Cl)cc2c1C1CCN(CC1)C1Cc2cccc3cccc1c23 Show InChI InChI=1S/C26H25ClN2/c1-16-25(22-15-20(27)8-9-23(22)28-16)18-10-12-29(13-11-18)24-14-19-6-2-4-17-5-3-7-21(24)26(17)19/h2-9,15,18,24,28H,10-14H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	680	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]U-69593 from kappa opioid receptor expressed in HEK293 cells				Bioorg Med Chem Lett 16: 3524-8 (2006) Article DOI: 10.1016/j.bmcl.2006.03.094 BindingDB Entry DOI: 10.7270/Q2VT1RQJ
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50185796 (5-chloro-3-(1-(1,2-dihydroacenaphthylen-1-yl)piper...) Show SMILES Cc1[nH]c2ccc(Cl)cc2c1C1CCN(CC1)C1Cc2cccc3cccc1c23 Show InChI InChI=1S/C26H25ClN2/c1-16-25(22-15-20(27)8-9-23(22)28-16)18-10-12-29(13-11-18)24-14-19-6-2-4-17-5-3-7-21(24)26(17)19/h2-9,15,18,24,28H,10-14H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.75E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]DDPDE from delta opioid receptor expressed in HEK293 cells				Bioorg Med Chem Lett 16: 3524-8 (2006) Article DOI: 10.1016/j.bmcl.2006.03.094 BindingDB Entry DOI: 10.7270/Q2VT1RQJ
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50185796 (5-chloro-3-(1-(1,2-dihydroacenaphthylen-1-yl)piper...) Show SMILES Cc1[nH]c2ccc(Cl)cc2c1C1CCN(CC1)C1Cc2cccc3cccc1c23 Show InChI InChI=1S/C26H25ClN2/c1-16-25(22-15-20(27)8-9-23(22)28-16)18-10-12-29(13-11-18)24-14-19-6-2-4-17-5-3-7-21(24)26(17)19/h2-9,15,18,24,28H,10-14H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	5.46E+4	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Agonist activity at ORL1 receptor expressed in HEK293 cells by calciun flux assay				Bioorg Med Chem Lett 16: 3524-8 (2006) Article DOI: 10.1016/j.bmcl.2006.03.094 BindingDB Entry DOI: 10.7270/Q2VT1RQJ
					More data for this Ligand-Target Pair