BDBM50185798 7-chloro-3-(1-(cyclooctylmethyl)piperidin-4-yl)-1H-indole::CHEMBL427395

SMILES: Clc1cccc2c(c[nH]c12)C1CCN(CC2CCCCCCC2)CC1

InChI Key: InChIKey=PFOKKLNWASJYSD-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50185798   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50185798 (7-chloro-3-(1-(cyclooctylmethyl)piperidin-4-yl)-1H...) Show SMILES Clc1cccc2c(c[nH]c12)C1CCN(CC2CCCCCCC2)CC1 Show InChI InChI=1S/C22H31ClN2/c23-21-10-6-9-19-20(15-24-22(19)21)18-11-13-25(14-12-18)16-17-7-4-2-1-3-5-8-17/h6,9-10,15,17-18,24H,1-5,7-8,11-14,16H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	430	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from mu opioid receptor expressed in HEK293 cells				Bioorg Med Chem Lett 16: 3524-8 (2006) Article DOI: 10.1016/j.bmcl.2006.03.094 BindingDB Entry DOI: 10.7270/Q2VT1RQJ
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50185798 (7-chloro-3-(1-(cyclooctylmethyl)piperidin-4-yl)-1H...) Show SMILES Clc1cccc2c(c[nH]c12)C1CCN(CC2CCCCCCC2)CC1 Show InChI InChI=1S/C22H31ClN2/c23-21-10-6-9-19-20(15-24-22(19)21)18-11-13-25(14-12-18)16-17-7-4-2-1-3-5-8-17/h6,9-10,15,17-18,24H,1-5,7-8,11-14,16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	660	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Agonist activity at ORL1 receptor expressed in HEK293 cells by calciun flux assay				Bioorg Med Chem Lett 16: 3524-8 (2006) Article DOI: 10.1016/j.bmcl.2006.03.094 BindingDB Entry DOI: 10.7270/Q2VT1RQJ
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50185798 (7-chloro-3-(1-(cyclooctylmethyl)piperidin-4-yl)-1H...) Show SMILES Clc1cccc2c(c[nH]c12)C1CCN(CC2CCCCCCC2)CC1 Show InChI InChI=1S/C22H31ClN2/c23-21-10-6-9-19-20(15-24-22(19)21)18-11-13-25(14-12-18)16-17-7-4-2-1-3-5-8-17/h6,9-10,15,17-18,24H,1-5,7-8,11-14,16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.17E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]U-69593 from kappa opioid receptor expressed in HEK293 cells				Bioorg Med Chem Lett 16: 3524-8 (2006) Article DOI: 10.1016/j.bmcl.2006.03.094 BindingDB Entry DOI: 10.7270/Q2VT1RQJ
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50185798 (7-chloro-3-(1-(cyclooctylmethyl)piperidin-4-yl)-1H...) Show SMILES Clc1cccc2c(c[nH]c12)C1CCN(CC2CCCCCCC2)CC1 Show InChI InChI=1S/C22H31ClN2/c23-21-10-6-9-19-20(15-24-22(19)21)18-11-13-25(14-12-18)16-17-7-4-2-1-3-5-8-17/h6,9-10,15,17-18,24H,1-5,7-8,11-14,16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]DDPDE from delta opioid receptor expressed in HEK293 cells				Bioorg Med Chem Lett 16: 3524-8 (2006) Article DOI: 10.1016/j.bmcl.2006.03.094 BindingDB Entry DOI: 10.7270/Q2VT1RQJ
					More data for this Ligand-Target Pair