BDBM50185812 2-(3-(1-(1,2-dihydroacenaphthylen-1-yl)piperidin-4-yl)-1H-pyrrolo[2,3-b]pyridin-1-yl)ethanol::CHEMBL212630

SMILES: OCCn1cc(C2CCN(CC2)C2Cc3cccc4cccc2c34)c2cccnc12

InChI Key: InChIKey=KQNPGUMEIULVJR-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50185812   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nociceptin receptor (Homo sapiens (Human))	BDBM50185812 (2-(3-(1-(1,2-dihydroacenaphthylen-1-yl)piperidin-4...) Show SMILES OCCn1cc(C2CCN(CC2)C2Cc3cccc4cccc2c34)c2cccnc12 Show InChI InChI=1S/C26H27N3O/c30-15-14-29-17-23(21-8-3-11-27-26(21)29)18-9-12-28(13-10-18)24-16-20-6-1-4-19-5-2-7-22(24)25(19)20/h1-8,11,17-18,24,30H,9-10,12-16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	94	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Agonist activity at ORL1 receptor expressed in HEK293 cells by calciun flux assay				Bioorg Med Chem Lett 16: 3524-8 (2006) Article DOI: 10.1016/j.bmcl.2006.03.094 BindingDB Entry DOI: 10.7270/Q2VT1RQJ
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50185812 (2-(3-(1-(1,2-dihydroacenaphthylen-1-yl)piperidin-4...) Show SMILES OCCn1cc(C2CCN(CC2)C2Cc3cccc4cccc2c34)c2cccnc12 Show InChI InChI=1S/C26H27N3O/c30-15-14-29-17-23(21-8-3-11-27-26(21)29)18-9-12-28(13-10-18)24-16-20-6-1-4-19-5-2-7-22(24)25(19)20/h1-8,11,17-18,24,30H,9-10,12-16H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	530	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from mu opioid receptor expressed in HEK293 cells				Bioorg Med Chem Lett 16: 3524-8 (2006) Article DOI: 10.1016/j.bmcl.2006.03.094 BindingDB Entry DOI: 10.7270/Q2VT1RQJ
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50185812 (2-(3-(1-(1,2-dihydroacenaphthylen-1-yl)piperidin-4...) Show SMILES OCCn1cc(C2CCN(CC2)C2Cc3cccc4cccc2c34)c2cccnc12 Show InChI InChI=1S/C26H27N3O/c30-15-14-29-17-23(21-8-3-11-27-26(21)29)18-9-12-28(13-10-18)24-16-20-6-1-4-19-5-2-7-22(24)25(19)20/h1-8,11,17-18,24,30H,9-10,12-16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]U-69593 from kappa opioid receptor expressed in HEK293 cells				Bioorg Med Chem Lett 16: 3524-8 (2006) Article DOI: 10.1016/j.bmcl.2006.03.094 BindingDB Entry DOI: 10.7270/Q2VT1RQJ
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50185812 (2-(3-(1-(1,2-dihydroacenaphthylen-1-yl)piperidin-4...) Show SMILES OCCn1cc(C2CCN(CC2)C2Cc3cccc4cccc2c34)c2cccnc12 Show InChI InChI=1S/C26H27N3O/c30-15-14-29-17-23(21-8-3-11-27-26(21)29)18-9-12-28(13-10-18)24-16-20-6-1-4-19-5-2-7-22(24)25(19)20/h1-8,11,17-18,24,30H,9-10,12-16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]DDPDE from delta opioid receptor expressed in HEK293 cells				Bioorg Med Chem Lett 16: 3524-8 (2006) Article DOI: 10.1016/j.bmcl.2006.03.094 BindingDB Entry DOI: 10.7270/Q2VT1RQJ
					More data for this Ligand-Target Pair