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BDBM50185824 CHEMBL3824243

SMILES: CC[C@H](Nc1nccc(Nc2cc([nH]n2)C2CC2)n1)c1ccc2[nH]ccc2n1

InChI Key: InChIKey=QWFHISYETQDHDU-ZDUSSCGKSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50185824   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Serine/threonine-protein kinase PAK 1


(Homo sapiens (Human))		BDBM50185824
PNG
(CHEMBL3824243)
Show SMILES CC[C@H](Nc1nccc(Nc2cc([nH]n2)C2CC2)n1)c1ccc2[nH]ccc2n1 |r|
Show InChI InChI=1S/C20H22N8/c1-2-13(15-6-5-14-16(23-15)7-9-21-14)24-20-22-10-8-18(26-20)25-19-11-17(27-28-19)12-3-4-12/h5-13,21H,2-4H2,1H3,(H3,22,24,25,26,27,28)/t13-/m0/s1
PDB

UniProtKB/SwissProt
UniProtKB/TrEMBL

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CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
 23n/an/an/an/an/an/an/an/a



Genentech

Curated by ChEMBL


Assay Description
Inhibition of recombinant human GST-tagged PAK1 kinase domain expressed in baculovirus expression system assessed as suppression of phosphorylation o...

Bioorg Med Chem Lett 26: 3518-24 (2016)


BindingDB Entry DOI: 10.7270/Q2KK9DQJ
More data for this
Ligand-Target Pair