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BDBM50185832 CHEMBL3822836

SMILES: C[C@H](Nc1nccc(Nc2cc([nH]n2)C2CC(F)(F)C2)n1)c1ccc2[nH]ccc2n1

InChI Key: InChIKey=DTIPYTJPPYYCBX-NSHDSACASA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50185832   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Serine/threonine-protein kinase PAK 1


(Homo sapiens (Human))		BDBM50185832
PNG
(CHEMBL3822836)
Show SMILES C[C@H](Nc1nccc(Nc2cc([nH]n2)C2CC(F)(F)C2)n1)c1ccc2[nH]ccc2n1 |r|
Show InChI InChI=1S/C20H20F2N8/c1-11(13-2-3-14-15(26-13)4-6-23-14)25-19-24-7-5-17(28-19)27-18-8-16(29-30-18)12-9-20(21,22)10-12/h2-8,11-12,23H,9-10H2,1H3,(H3,24,25,27,28,29,30)/t11-/m0/s1
PDB

UniProtKB/SwissProt
UniProtKB/TrEMBL

antibodypedia
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CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
 68n/an/an/an/an/an/an/an/a



Genentech

Curated by ChEMBL


Assay Description
Inhibition of recombinant human GST-tagged PAK1 kinase domain expressed in baculovirus expression system assessed as suppression of phosphorylation o...

Bioorg Med Chem Lett 26: 3518-24 (2016)


BindingDB Entry DOI: 10.7270/Q2KK9DQJ
More data for this
Ligand-Target Pair