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SMILES: Fc1ccc(cc1)-n1nc(cc1NS(=O)(=O)c1ccc(s1)-c1cc(on1)C(F)(F)F)-c1cccs1

InChI Key: InChIKey=AQBWKNOCZBYHHS-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50185942   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Peroxisome proliferator-activated receptor gamma


(Homo sapiens (Human))		BDBM50185942
PNG
((N-[1-(4-fluorophenyl)-3-(2-thienyl)-1H-pyrazol-5-...)
Show SMILES Fc1ccc(cc1)-n1nc(cc1NS(=O)(=O)c1ccc(s1)-c1cc(on1)C(F)(F)F)-c1cccs1
Show InChI InChI=1S/C21H12F4N4O3S3/c22-12-3-5-13(6-4-12)29-19(11-14(26-29)16-2-1-9-33-16)28-35(30,31)20-8-7-17(34-20)15-10-18(32-27-15)21(23,24)25/h1-11,28H
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MMDB

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PC cid
PC sid
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Article
PubMed
n/an/a 175n/an/an/an/an/an/a



National Health Research Institutes

Curated by ChEMBL


Assay Description
Displacement of [3H]rosiglitazone from PPARgamma by SPA

J Med Chem 49: 2703-12 (2006)


Article DOI: 10.1021/jm051129s
BindingDB Entry DOI: 10.7270/Q2736QHH
More data for this
Ligand-Target Pair