BDBM50185986 1,6-Bis(4'-hydroxyphenyl)-hexa-1,3,5-triene::CHEMBL381731

SMILES: Oc1ccc(\C=C\C=C\C=C\c2ccc(O)cc2)cc1

InChI Key: InChIKey=FXGYAFMJWIVHGO-CRQXNEITSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50185986   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM50185986 (1,6-Bis(4'-hydroxyphenyl)-hexa-1,3,5-triene | CHEM...) Show SMILES Oc1ccc(\C=C\C=C\C=C\c2ccc(O)cc2)cc1 Show InChI InChI=1S/C18H16O2/c19-17-11-7-15(8-12-17)5-3-1-2-4-6-16-9-13-18(20)14-10-16/h1-14,19-20H/b2-1+,5-3+,6-4+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Displacement of [125I]2-(4'-dimethylaminophenyl)-6-iodoimidazo[1,2-a]pyridine from beta amyloid peptide in brain tissue at 50 uL				J Med Chem 49: 2841-4 (2006) Article DOI: 10.1021/jm051020k BindingDB Entry DOI: 10.7270/Q2Q23ZT9
					More data for this Ligand-Target Pair
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM50185986 (1,6-Bis(4'-hydroxyphenyl)-hexa-1,3,5-triene | CHEM...) Show SMILES Oc1ccc(\C=C\C=C\C=C\c2ccc(O)cc2)cc1 Show InChI InChI=1S/C18H16O2/c19-17-11-7-15(8-12-17)5-3-1-2-4-6-16-9-13-18(20)14-10-16/h1-14,19-20H/b2-1+,5-3+,6-4+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Displacement of [125I](E,E)-1-iodo-2,5-bis-(3-hydroxycarbonyl-4-methoxy)styrylbenzene from beta amyloid peptide in brain tissue at 50 uL				J Med Chem 49: 2841-4 (2006) Article DOI: 10.1021/jm051020k BindingDB Entry DOI: 10.7270/Q2Q23ZT9
					More data for this Ligand-Target Pair