BDBM50186054 4-((3,5-dichloro-N-(5-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)thiazol-2-yl)benzamido)methyl)benzoic acid::CHEMBL379161

SMILES: OC(=O)c1ccc(CN(C(=O)c2cc(Cl)cc(Cl)c2)c2ncc(s2)C(O)(C(F)(F)F)C(F)(F)F)cc1

InChI Key: InChIKey=QAWWDKODHQYNBE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50186054   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human))	BDBM50186054 (4-((3,5-dichloro-N-(5-(1,1,1,3,3,3-hexafluoro-2-hy...) Show SMILES OC(=O)c1ccc(CN(C(=O)c2cc(Cl)cc(Cl)c2)c2ncc(s2)C(O)(C(F)(F)F)C(F)(F)F)cc1 Show InChI InChI=1S/C21H12Cl2F6N2O4S/c22-13-5-12(6-14(23)7-13)16(32)31(9-10-1-3-11(4-2-10)17(33)34)18-30-8-15(36-18)19(35,20(24,25)26)21(27,28)29/h1-8,35H,9H2,(H,33,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharma LLC. Curated by ChEMBL					Assay Description Inhibition of MCD				Bioorg Med Chem Lett 16: 3484-8 (2006) Article DOI: 10.1016/j.bmcl.2006.03.100 BindingDB Entry DOI: 10.7270/Q2FJ2GCN
					More data for this Ligand-Target Pair