BDBM50186124 CHEMBL410087::N-((R)-3-(4-chlorophenyl)-1-(4-(1-cyclohexyl-2-(N-ethylmethan-4-ylsulfonamido)ethyl)piperazin-1-yl)-1-oxopropan-2-yl)-2-(indolin-2-yl)acetamide

SMILES: CCN(CC(C1CCCCC1)N1CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)CC1Cc2ccccc2N1)S(C)(=O)=O

InChI Key: InChIKey=RZXIDOYEKBWJOX-FURWPUMCSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50186124   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50186124 (CHEMBL410087 | N-((R)-3-(4-chlorophenyl)-1-(4-(1-c...) Show SMILES CCN(CC(C1CCCCC1)N1CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)CC1Cc2ccccc2N1)S(C)(=O)=O Show InChI InChI=1S/C34H48ClN5O4S/c1-3-40(45(2,43)44)24-32(26-9-5-4-6-10-26)38-17-19-39(20-18-38)34(42)31(21-25-13-15-28(35)16-14-25)37-33(41)23-29-22-27-11-7-8-12-30(27)36-29/h7-8,11-16,26,29,31-32,36H,3-6,9-10,17-24H2,1-2H3,(H,37,41)/t29?,31-,32?/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [125]I-NDP-alpha-MSH binding to human MC4R transfected in HEK293 cells				Bioorg Med Chem Lett 16: 3449-53 (2006) Article DOI: 10.1016/j.bmcl.2006.04.002 BindingDB Entry DOI: 10.7270/Q2ST7PFS
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50186124 (CHEMBL410087 | N-((R)-3-(4-chlorophenyl)-1-(4-(1-c...) Show SMILES CCN(CC(C1CCCCC1)N1CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)CC1Cc2ccccc2N1)S(C)(=O)=O Show InChI InChI=1S/C34H48ClN5O4S/c1-3-40(45(2,43)44)24-32(26-9-5-4-6-10-26)38-17-19-39(20-18-38)34(42)31(21-25-13-15-28(35)16-14-25)37-33(41)23-29-22-27-11-7-8-12-30(27)36-29/h7-8,11-16,26,29,31-32,36H,3-6,9-10,17-24H2,1-2H3,(H,37,41)/t29?,31-,32?/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [125]I-NDP-alpha-MSH binding to human MC4R transfected in HEK293 cells				Bioorg Med Chem Lett 16: 3449-53 (2006) Article DOI: 10.1016/j.bmcl.2006.04.002 BindingDB Entry DOI: 10.7270/Q2ST7PFS
					More data for this Ligand-Target Pair