BDBM50186141 2-cyanoethyl N-({3-[4-hydroxy-1-(3-methylbutyl)-2-oxo-1,2-dihydro-1,8-naphthyridin-3-yl]-1,1-dioxo-4H-1,2,4-benzothiadiazin-7-yl}sulfamoyl)carbamate::CHEMBL210854

SMILES: CC(C)CCn1c2ncccc2c(O)c(C2=Nc3ccc(NS(=O)(=O)NC(=O)OCCC#N)cc3S(=O)(=O)N2)c1=O

InChI Key: InChIKey=SHZGGQLSBNQZLM-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50186141   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatitis C virus NS5B RNA-dependent RNA polymerase (Hepatitis C virus)	BDBM50186141 (2-cyanoethyl N-({3-[4-hydroxy-1-(3-methylbutyl)-2-...) Show SMILES CC(C)CCn1c2ncccc2c(O)c(C2=Nc3ccc(NS(=O)(=O)NC(=O)OCCC#N)cc3S(=O)(=O)N2)c1=O |t:16| Show InChI InChI=1S/C24H25N7O8S2/c1-14(2)8-11-31-22-16(5-3-10-26-22)20(32)19(23(31)33)21-27-17-7-6-15(13-18(17)40(35,36)29-21)28-41(37,38)30-24(34)39-12-4-9-25/h3,5-7,10,13-14,28,32H,4,8,11-12H2,1-2H3,(H,27,29)(H,30,34)	UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.70	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of HCV 1b NS5B RNA polymerase				Bioorg Med Chem Lett 16: 3367-70 (2006) Article DOI: 10.1016/j.bmcl.2006.04.015 BindingDB Entry DOI: 10.7270/Q2P26XQC
					More data for this Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase (Hepatitis C virus)	BDBM50186141 (2-cyanoethyl N-({3-[4-hydroxy-1-(3-methylbutyl)-2-...) Show SMILES CC(C)CCn1c2ncccc2c(O)c(C2=Nc3ccc(NS(=O)(=O)NC(=O)OCCC#N)cc3S(=O)(=O)N2)c1=O |t:16| Show InChI InChI=1S/C24H25N7O8S2/c1-14(2)8-11-31-22-16(5-3-10-26-22)20(32)19(23(31)33)21-27-17-7-6-15(13-18(17)40(35,36)29-21)28-41(37,38)30-24(34)39-12-4-9-25/h3,5-7,10,13-14,28,32H,4,8,11-12H2,1-2H3,(H,27,29)(H,30,34)	UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of HCV 1a NS5B RNA polymerase				Bioorg Med Chem Lett 16: 3367-70 (2006) Article DOI: 10.1016/j.bmcl.2006.04.015 BindingDB Entry DOI: 10.7270/Q2P26XQC
					More data for this Ligand-Target Pair