BDBM50186147 CHEMBL210050::N-benzyl({3-[4-hydroxy-1-(3-methylbutyl)-2-oxo-1,2-dihydro-1,8-naphthyridin-3-yl]-1,1-dioxo-4H-1,2,4-benzothiadiazin-7-yl}amino)sulfonamide

SMILES: CC(C)CCn1c2ncccc2c(O)c(C2=Nc3ccc(NS(=O)(=O)NCc4ccccc4)cc3S(=O)(=O)N2)c1=O

InChI Key: InChIKey=MGHVKDXRIBJWRN-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50186147   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatitis C virus NS5B RNA-dependent RNA polymerase (Hepatitis C virus)	BDBM50186147 (CHEMBL210050 | N-benzyl({3-[4-hydroxy-1-(3-methylb...) Show SMILES CC(C)CCn1c2ncccc2c(O)c(C2=Nc3ccc(NS(=O)(=O)NCc4ccccc4)cc3S(=O)(=O)N2)c1=O |t:16| Show InChI InChI=1S/C27H28N6O6S2/c1-17(2)12-14-33-26-20(9-6-13-28-26)24(34)23(27(33)35)25-30-21-11-10-19(15-22(21)40(36,37)32-25)31-41(38,39)29-16-18-7-4-3-5-8-18/h3-11,13,15,17,29,31,34H,12,14,16H2,1-2H3,(H,30,32)	UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.5	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of HCV 1a NS5B RNA polymerase				Bioorg Med Chem Lett 16: 3367-70 (2006) Article DOI: 10.1016/j.bmcl.2006.04.015 BindingDB Entry DOI: 10.7270/Q2P26XQC
					More data for this Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase (Hepatitis C virus)	BDBM50186147 (CHEMBL210050 | N-benzyl({3-[4-hydroxy-1-(3-methylb...) Show SMILES CC(C)CCn1c2ncccc2c(O)c(C2=Nc3ccc(NS(=O)(=O)NCc4ccccc4)cc3S(=O)(=O)N2)c1=O |t:16| Show InChI InChI=1S/C27H28N6O6S2/c1-17(2)12-14-33-26-20(9-6-13-28-26)24(34)23(27(33)35)25-30-21-11-10-19(15-22(21)40(36,37)32-25)31-41(38,39)29-16-18-7-4-3-5-8-18/h3-11,13,15,17,29,31,34H,12,14,16H2,1-2H3,(H,30,32)	UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of HCV 1b NS5B RNA polymerase				Bioorg Med Chem Lett 16: 3367-70 (2006) Article DOI: 10.1016/j.bmcl.2006.04.015 BindingDB Entry DOI: 10.7270/Q2P26XQC
					More data for this Ligand-Target Pair