BDBM50186150 CHEMBL208740::N-{3-[4-hydroxy-1-(3-methylbutyl)-2-oxo-1,2-dihydro-1,8-naphthyridin-3-yl]-1,1-dioxo-4H-1,2,4-benzothiadiazin-7-yl}aminosulfonamide

SMILES: CC(C)CCn1c2ncccc2c(O)c(C2=Nc3ccc(NS(N)(=O)=O)cc3S(=O)(=O)N2)c1=O

InChI Key: InChIKey=SKCSOGGZVODZAP-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50186150   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatitis C virus NS5B RNA-dependent RNA polymerase (Hepatitis C virus)	BDBM50186150 (CHEMBL208740 | N-{3-[4-hydroxy-1-(3-methylbutyl)-2...) Show SMILES CC(C)CCn1c2ncccc2c(O)c(C2=Nc3ccc(NS(N)(=O)=O)cc3S(=O)(=O)N2)c1=O |t:16| Show InChI InChI=1S/C20H22N6O6S2/c1-11(2)7-9-26-19-13(4-3-8-22-19)17(27)16(20(26)28)18-23-14-6-5-12(24-34(21,31)32)10-15(14)33(29,30)25-18/h3-6,8,10-11,24,27H,7,9H2,1-2H3,(H,23,25)(H2,21,31,32)	UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of HCV 1a NS5B RNA polymerase				Bioorg Med Chem Lett 16: 3367-70 (2006) Article DOI: 10.1016/j.bmcl.2006.04.015 BindingDB Entry DOI: 10.7270/Q2P26XQC
					More data for this Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase (Hepatitis C virus)	BDBM50186150 (CHEMBL208740 | N-{3-[4-hydroxy-1-(3-methylbutyl)-2...) Show SMILES CC(C)CCn1c2ncccc2c(O)c(C2=Nc3ccc(NS(N)(=O)=O)cc3S(=O)(=O)N2)c1=O |t:16| Show InChI InChI=1S/C20H22N6O6S2/c1-11(2)7-9-26-19-13(4-3-8-22-19)17(27)16(20(26)28)18-23-14-6-5-12(24-34(21,31)32)10-15(14)33(29,30)25-18/h3-6,8,10-11,24,27H,7,9H2,1-2H3,(H,23,25)(H2,21,31,32)	UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.80	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of HCV 1b NS5B RNA polymerase				Bioorg Med Chem Lett 16: 3367-70 (2006) Article DOI: 10.1016/j.bmcl.2006.04.015 BindingDB Entry DOI: 10.7270/Q2P26XQC
					More data for this Ligand-Target Pair