BDBM50186153 CHEMBL210158::N-{3-[4-Hydroxy-1-(3-methyl-butyl)-2-oxo-1,2-dihydro-[1,8]naphthyridin-3-yl]-1,1-dioxo-1,4-dihydro-1lambda6-benzo[1,2,4]thiadiazin-7-yl}-methanesulfonamide::N-{3-[4-hydroxy-1-(3-methyl-butyl)-2-oxo-1,2-dihydro-[1,8]naphthyridin-3-yl]-1,1-dioxo-1,4-dihydro-1lambda*6*-benzo[1,2,4]thiadiazin-7-yl}-methanesulfonamide::N-{3-[4-hydroxy-1-(3-methyl-butyl)-2-oxo-1,2-dihydro-quinolin-3-yl]-1,1-dioxo-1,4-dihydro-1lambda*6*-benzo[1,2,4]thiadiazin-7-yl}-methanesulfonamide

SMILES: CC(C)CCn1c2ncccc2c(O)c(C2=Nc3ccc(NS(C)(=O)=O)cc3S(=O)(=O)N2)c1=O

InChI Key: InChIKey=GEATWBBNAXBKPV-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50186153   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatitis C virus NS5B RNA-dependent RNA polymerase (Hepatitis C virus)	BDBM50186153 (CHEMBL210158 | N-{3-[4-Hydroxy-1-(3-methyl-butyl)-...) Show SMILES CC(C)CCn1c2ncccc2c(O)c(C2=Nc3ccc(NS(C)(=O)=O)cc3S(=O)(=O)N2)c1=O |t:16| Show InChI InChI=1S/C21H23N5O6S2/c1-12(2)8-10-26-20-14(5-4-9-22-20)18(27)17(21(26)28)19-23-15-7-6-13(24-33(3,29)30)11-16(15)34(31,32)25-19/h4-7,9,11-12,24,27H,8,10H2,1-3H3,(H,23,25)	UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of HCV 1a NS5B RNA polymerase				Bioorg Med Chem Lett 16: 3367-70 (2006) Article DOI: 10.1016/j.bmcl.2006.04.015 BindingDB Entry DOI: 10.7270/Q2P26XQC
					More data for this Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase (Hepatitis C virus)	BDBM50186153 (CHEMBL210158 | N-{3-[4-Hydroxy-1-(3-methyl-butyl)-...) Show SMILES CC(C)CCn1c2ncccc2c(O)c(C2=Nc3ccc(NS(C)(=O)=O)cc3S(=O)(=O)N2)c1=O |t:16| Show InChI InChI=1S/C21H23N5O6S2/c1-12(2)8-10-26-20-14(5-4-9-22-20)18(27)17(21(26)28)19-23-15-7-6-13(24-33(3,29)30)11-16(15)34(31,32)25-19/h4-7,9,11-12,24,27H,8,10H2,1-3H3,(H,23,25)	UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of HCV 1b NS5B RNA polymerase				Bioorg Med Chem Lett 16: 3833-8 (2006) Article DOI: 10.1016/j.bmcl.2006.04.022 BindingDB Entry DOI: 10.7270/Q2J9660F
					More data for this Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase (Hepatitis C virus)	BDBM50186153 (CHEMBL210158 | N-{3-[4-Hydroxy-1-(3-methyl-butyl)-...) Show SMILES CC(C)CCn1c2ncccc2c(O)c(C2=Nc3ccc(NS(C)(=O)=O)cc3S(=O)(=O)N2)c1=O |t:16| Show InChI InChI=1S/C21H23N5O6S2/c1-12(2)8-10-26-20-14(5-4-9-22-20)18(27)17(21(26)28)19-23-15-7-6-13(24-33(3,29)30)11-16(15)34(31,32)25-19/h4-7,9,11-12,24,27H,8,10H2,1-3H3,(H,23,25)	UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of HCV 1a NS5B RNA polymerase				Bioorg Med Chem Lett 16: 3833-8 (2006) Article DOI: 10.1016/j.bmcl.2006.04.022 BindingDB Entry DOI: 10.7270/Q2J9660F
					More data for this Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase (Hepatitis C virus)	BDBM50186153 (CHEMBL210158 | N-{3-[4-Hydroxy-1-(3-methyl-butyl)-...) Show SMILES CC(C)CCn1c2ncccc2c(O)c(C2=Nc3ccc(NS(C)(=O)=O)cc3S(=O)(=O)N2)c1=O |t:16| Show InChI InChI=1S/C21H23N5O6S2/c1-12(2)8-10-26-20-14(5-4-9-22-20)18(27)17(21(26)28)19-23-15-7-6-13(24-33(3,29)30)11-16(15)34(31,32)25-19/h4-7,9,11-12,24,27H,8,10H2,1-3H3,(H,23,25)	UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of HCV 1b NS5B RNA polymerase				Bioorg Med Chem Lett 16: 3367-70 (2006) Article DOI: 10.1016/j.bmcl.2006.04.015 BindingDB Entry DOI: 10.7270/Q2P26XQC
					More data for this Ligand-Target Pair