BDBM50186180 7-{[(2-aminoethyl)sulfamoyl]amino}-3-[4-hydroxy-1-(3-methylbutyl)-2-oxo-1,2-dihydro-1,8-naphthyridin-3-yl]-4H-1,2,4-benzothiadiazine-1,1-dione::CHEMBL210671

SMILES: CC(C)CCn1c2ncccc2c(O)c(C2=Nc3ccc(NS(=O)(=O)NCCN)cc3S(=O)(=O)N2)c1=O

InChI Key: InChIKey=WOIARNYURGVZHM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50186180   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatitis C virus NS5B RNA-dependent RNA polymerase (Hepatitis C virus)	BDBM50186180 (7-{[(2-aminoethyl)sulfamoyl]amino}-3-[4-hydroxy-1-...) Show SMILES CC(C)CCn1c2ncccc2c(O)c(C2=Nc3ccc(NS(=O)(=O)NCCN)cc3S(=O)(=O)N2)c1=O |t:16| Show InChI InChI=1S/C22H27N7O6S2/c1-13(2)7-11-29-21-15(4-3-9-24-21)19(30)18(22(29)31)20-26-16-6-5-14(12-17(16)36(32,33)28-20)27-37(34,35)25-10-8-23/h3-6,9,12-13,25,27,30H,7-8,10-11,23H2,1-2H3,(H,26,28)	UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of HCV 1a NS5B RNA polymerase				Bioorg Med Chem Lett 16: 3367-70 (2006) Article DOI: 10.1016/j.bmcl.2006.04.015 BindingDB Entry DOI: 10.7270/Q2P26XQC
					More data for this Ligand-Target Pair