null
SMILES: CO[C@]12CC[C@@]3(C[C@@H]1[C@@](C)(O)C1CCC1)C1Cc4ccc(O)c5O[C@@H]2[C@]3(CCN1CC1CC1)c45
InChI Key: InChIKey=PGKKZFPBWMBKQG-VCWXTFISSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM50186209 (CHEMBL556964 | N-Cyclopropylmethyl-6,14-endoethano...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.84 | n/a | n/a | n/a | n/a |
KAIST Curated by ChEMBL | Assay Description Stimulation of [35S]GTP-gamma-S binding at kappa opioid receptor in human brain cortical membrane | Bioorg Med Chem Lett 16: 3609-13 (2006) Article DOI: 10.1016/j.bmcl.2006.02.017 BindingDB Entry DOI: 10.7270/Q2TQ629F | |||||||||||
More data for this Ligand-Target Pair |