BDBM50186221 CHEMBL3822759

SMILES: CC(C)(C)OC(=O)N1CCC(CC1)n1ncc2cc(ncc12)-c1ccc(cc1)S(C)(=O)=O

InChI Key: InChIKey=PJOSUSMXOUOJNU-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50186221   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucose-dependent insulinotropic receptor (Homo sapiens (Human))	BDBM50186221 (CHEMBL3822759) Show SMILES CC(C)(C)OC(=O)N1CCC(CC1)n1ncc2cc(ncc12)-c1ccc(cc1)S(C)(=O)=O Show InChI InChI=1S/C23H28N4O4S/c1-23(2,3)31-22(28)26-11-9-18(10-12-26)27-21-15-24-20(13-17(21)14-25-27)16-5-7-19(8-6-16)32(4,29)30/h5-8,13-15,18H,9-12H2,1-4H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	20	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Agonist activity at human GPR119 expressed in Flp-In-T-Rex-HEK293 cells assessed as stimulation of cAMP level measured after 30 mins by HTRF assay				Bioorg Med Chem 25: 4339-4354 (2017) Article DOI: 10.1016/j.bmc.2017.06.014 BindingDB Entry DOI: 10.7270/Q21V5HFG
					More data for this Ligand-Target Pair
G-protein coupled receptor 119 (GPR119) (Homo sapiens (Human))	BDBM50186221 (CHEMBL3822759) Show SMILES CC(C)(C)OC(=O)N1CCC(CC1)n1ncc2cc(ncc12)-c1ccc(cc1)S(C)(=O)=O Show InChI InChI=1S/C23H28N4O4S/c1-23(2,3)31-22(28)26-11-9-18(10-12-26)27-21-15-24-20(13-17(21)14-25-27)16-5-7-19(8-6-16)32(4,29)30/h5-8,13-15,18H,9-12H2,1-4H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	20	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Agonist activity at human GPR119 expressed in Flp-In-T-Rex-HEK293 cells after 30 mins by cAMP accumulation assay				Bioorg Med Chem Lett 26: 3441-6 (2016) BindingDB Entry DOI: 10.7270/Q2XW4MRS
					More data for this Ligand-Target Pair