BDBM50186281 (6-(3-(piperidin-1-yl)propoxy)-3,4-dihydroisoquinolin-2(1H)-yl)(thiophen-2-yl)methanone::CHEMBL377099
SMILES: O=C(N1CCc2cc(OCCCN3CCCCC3)ccc2C1)c1cccs1
InChI Key: InChIKey=ZEIOZVCYDANZRX-UHFFFAOYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Histamine H3 receptor (Homo sapiens (Human)) | BDBM50186281 ((6-(3-(piperidin-1-yl)propoxy)-3,4-dihydroisoquino...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 2.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Displacement of [3H]N-alpha-methylhistamine from human cloned H3 receptor | Bioorg Med Chem Lett 16: 3415-8 (2006) Article DOI: 10.1016/j.bmcl.2006.04.004 BindingDB Entry DOI: 10.7270/Q2WM1D07 | |||||||||||
More data for this Ligand-Target Pair |