BDBM50186360 CHEMBL209753::N-(1-benzylpiperidin-4-yl)-3-(5-(4-(piperidin-1-yl)piperidin-1-yl)-1H-benzo[d]imidazol-2-yl)-1H-indazol-5-amine

SMILES: C(N1CCC(CC1)Nc1ccc2[nH]nc(-c3nc4ccc(cc4[nH]3)N3CCC(CC3)N3CCCCC3)c2c1)c1ccccc1

InChI Key: InChIKey=GGFQIKFJFWLNNJ-UHFFFAOYSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50186360   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bcr-Abl (Homo sapiens (Human))	BDBM50186360 (CHEMBL209753 | N-(1-benzylpiperidin-4-yl)-3-(5-(4-...) Show SMILES C(N1CCC(CC1)Nc1ccc2[nH]nc(-c3nc4ccc(cc4[nH]3)N3CCC(CC3)N3CCCCC3)c2c1)c1ccccc1 Show InChI InChI=1S/C36H44N8/c1-3-7-26(8-4-1)25-42-19-13-27(14-20-42)37-28-9-11-32-31(23-28)35(41-40-32)36-38-33-12-10-30(24-34(33)39-36)44-21-15-29(16-22-44)43-17-5-2-6-18-43/h1,3-4,7-12,23-24,27,29,37H,2,5-6,13-22,25H2,(H,38,39)(H,40,41)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	70	n/a	n/a	n/a	n/a
Chiron Corporation Curated by ChEMBL					Assay Description Antiproliferative activity against K562 cells expressing Bcr-Abl				Bioorg Med Chem Lett 16: 3789-92 (2006) Article DOI: 10.1016/j.bmcl.2006.04.043 BindingDB Entry DOI: 10.7270/Q2HD7WG3
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Homo sapiens (Human))	BDBM50186360 (CHEMBL209753 | N-(1-benzylpiperidin-4-yl)-3-(5-(4-...) Show SMILES C(N1CCC(CC1)Nc1ccc2[nH]nc(-c3nc4ccc(cc4[nH]3)N3CCC(CC3)N3CCCCC3)c2c1)c1ccccc1 Show InChI InChI=1S/C36H44N8/c1-3-7-26(8-4-1)25-42-19-13-27(14-20-42)37-28-9-11-32-31(23-28)35(41-40-32)36-38-33-12-10-30(24-34(33)39-36)44-21-15-29(16-22-44)43-17-5-2-6-18-43/h1,3-4,7-12,23-24,27,29,37H,2,5-6,13-22,25H2,(H,38,39)(H,40,41)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Chiron Corporation Curated by ChEMBL					Assay Description Inhibition of c-ABL				Bioorg Med Chem Lett 16: 3789-92 (2006) Article DOI: 10.1016/j.bmcl.2006.04.043 BindingDB Entry DOI: 10.7270/Q2HD7WG3
					More data for this Ligand-Target Pair