BDBM50186416 3-(4-(5-(5-chloro-6-isopropoxypyridin-3-yl)-1,3,4-oxadiazol-2-yl)-3-methylphenyl)propanoic acid::CHEMBL378562

SMILES: CC(C)Oc1ncc(cc1Cl)-c1nnc(o1)-c1ccc(CCC(O)=O)cc1C

InChI Key: InChIKey=POGKUYUDXQCYOH-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50186416   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM50186416 (3-(4-(5-(5-chloro-6-isopropoxypyridin-3-yl)-1,3,4-...) Show SMILES CC(C)Oc1ncc(cc1Cl)-c1nnc(o1)-c1ccc(CCC(O)=O)cc1C Show InChI InChI=1S/C20H20ClN3O4/c1-11(2)27-20-16(21)9-14(10-22-20)18-23-24-19(28-18)15-6-4-13(8-12(15)3)5-7-17(25)26/h4,6,8-11H,5,7H2,1-3H3,(H,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	19	n/a	n/a	n/a	n/a
Merck & Co. Curated by ChEMBL					Assay Description Agonist activity at S1P1 receptor assessed as induction of [35S]GTPgammaS binding				Bioorg Med Chem Lett 16: 3684-7 (2006) Article DOI: 10.1016/j.bmcl.2006.04.064 BindingDB Entry DOI: 10.7270/Q2HD7V7J
					More data for this Ligand-Target Pair